Survival Analysis
Colorectal Cancer | Ferroptosis | Unique Genes per RCD Type | Gene Expression of Tumor Samples
Mark Edward M. Gonzales1
Dr. Anish M.S. Shrestha2
I. Preliminaries
Loading libraries
library("tidyverse")
library("tibble")
library("msigdbr")
library("ggplot2")
library("TCGAbiolinks")
library("RNAseqQC")
library("DESeq2")
library("ensembldb")
library("purrr")
library("magrittr")
library("vsn")
library("matrixStats")
library("dplyr")
library("grex")
library("survminer")
library("survival")II. Downloading the TCGA gene expression data
Create a function for downloading TCGA gene expression data.
For more detailed documentation, refer to
2. Differential Gene Expression Analysis - TCGA.Rmd.
query_and_filter_samples <- function(project) {
query_tumor <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = "Primary Tumor"
)
tumor <- getResults(query_tumor)
query_normal <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = "Solid Tissue Normal"
)
normal <- getResults(query_normal)
submitter_ids <- inner_join(tumor, normal, by = "cases.submitter_id") %>%
dplyr::select(cases.submitter_id)
tumor <- tumor %>%
dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
normal <- normal %>%
dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
samples <- rbind(tumor, normal)
unique(samples$sample_type)
query_project <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = c("Solid Tissue Normal", "Primary Tumor"),
barcode = as.list(samples$sample.submitter_id)
)
# If this is your first time running this notebook (i.e., you have not yet downloaded the results of the query in the previous block),
# uncomment the line below
# GDCdownload(query_project)
return(list(samples = samples, query_project = query_project))
}Download the TCGA gene expression data for colorectal cancer (TCGA-COAD).
projects <- c("TCGA-COAD")
with_results_projects <- c()
samples <- list()
project_data <- list()
for (project in projects) {
result <- tryCatch(
{
result <- query_and_filter_samples(project)
samples[[project]] <- result$samples
project_data[[project]] <- result$query_project
with_results_projects <- c(with_results_projects, project)
},
error = function(e) {
}
)
}Running the code block above should generate and populate a directory
named GDCdata.
III. Data preprocessing
Construct the RNA-seq count matrix for each cancer type.
tcga_data <- list()
tcga_matrix <- list()
projects <- with_results_projects
for (project in projects) {
tcga_data[[project]] <- GDCprepare(project_data[[project]], summarizedExperiment = TRUE)
}for (project in projects) {
count_matrix <- assay(tcga_data[[project]], "unstranded")
# Remove duplicate entries
count_matrix_df <- data.frame(count_matrix)
count_matrix_df <- count_matrix_df[!duplicated(count_matrix_df), ]
count_matrix <- data.matrix(count_matrix_df)
rownames(count_matrix) <- cleanid(rownames(count_matrix))
count_matrix <- count_matrix[!(duplicated(rownames(count_matrix)) | duplicated(rownames(count_matrix), fromLast = TRUE)), ]
tcga_matrix[[project]] <- count_matrix
}Format the samples table so that it can be fed as input
to DESeq2.
for (project in projects) {
rownames(samples[[project]]) <- samples[[project]]$cases
samples[[project]] <- samples[[project]] %>%
dplyr::select(case = "cases.submitter_id", type = "sample_type")
samples[[project]]$type <- str_replace(samples[[project]]$type, "Solid Tissue Normal", "normal")
samples[[project]]$type <- str_replace(samples[[project]]$type, "Primary Tumor", "tumor")
}DESeq2 requires the row names of samples should be
identical to the column names of count_matrix.
for (project in projects) {
colnames(tcga_matrix[[project]]) <- gsub(x = colnames(tcga_matrix[[project]]), pattern = "\\.", replacement = "-")
tcga_matrix[[project]] <- tcga_matrix[[project]][, rownames(samples[[project]])]
# Sanity check
print(all(colnames(tcga_matrix[[project]]) == rownames(samples[[project]])))
}IV. Differential gene expression analysis
For more detailed documentation on obtaining the gene set, refer to
7. Differential Gene Expression Analysis - TCGA - Pan-cancer - Unique Genes.Rmd.
RCDdb <- "temp/unique_genes/necroptosis_ferroptosis_pyroptosis/"Write utility functions for filtering the gene sets, performing differential gene expression analysis, plotting the results, and performing variance-stabilizing transformation.
filter_gene_set_and_perform_dgea <- function(genes) {
tcga_rcd <- list()
for (project in projects) {
rownames(genes) <- genes$gene_id
tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
}
dds_rcd <- list()
res_rcd <- list()
for (project in projects) {
print(project)
print("=============")
dds <- DESeqDataSetFromMatrix(
countData = tcga_rcd[[project]],
colData = samples[[project]],
design = ~type
)
dds <- filter_genes(dds, min_count = 10)
dds$type <- relevel(dds$type, ref = "normal")
dds_rcd[[project]] <- DESeq(dds)
res_rcd[[project]] <- results(dds_rcd[[project]])
}
deseq.bbl.data <- list()
for (project in projects) {
deseq.results <- res_rcd[[project]]
deseq.bbl.data[[project]] <- data.frame(
row.names = rownames(deseq.results),
baseMean = deseq.results$baseMean,
log2FoldChange = deseq.results$log2FoldChange,
lfcSE = deseq.results$lfcSE,
stat = deseq.results$stat,
pvalue = deseq.results$pvalue,
padj = deseq.results$padj,
cancer_type = project,
gene_symbol = genes[rownames(deseq.results), "gene"]
)
}
deseq.bbl.data.combined <- bind_rows(deseq.bbl.data)
deseq.bbl.data.combined <- dplyr::filter(deseq.bbl.data.combined, abs(log2FoldChange) >= 1.5 & padj < 0.05)
return(deseq.bbl.data.combined)
}plot_dgea <- function(deseq.bbl.data.combined) {
sizes <- c("<10^-15" = 4, "10^-10" = 3, "10^-5" = 2, "0.05" = 1)
deseq.bbl.data.combined <- deseq.bbl.data.combined %>%
mutate(fdr_category = cut(padj,
breaks = c(-Inf, 1e-15, 1e-10, 1e-5, 0.05),
labels = c("<10^-15", "10^-10", "10^-5", "0.05"),
right = FALSE
))
top_genes <- deseq.bbl.data.combined %>%
group_by(cancer_type) %>%
mutate(rank = rank(-abs(log2FoldChange))) %>%
dplyr::filter(rank <= 10) %>%
ungroup()
ggplot(top_genes, aes(y = cancer_type, x = gene_symbol, size = fdr_category, fill = log2FoldChange)) +
geom_point(alpha = 0.5, shape = 21, color = "black") +
scale_size_manual(values = sizes) +
scale_fill_gradient2(low = "blue", mid = "white", high = "red", limits = c(min(deseq.bbl.data.combined$log2FoldChange), max(deseq.bbl.data.combined$log2FoldChange))) +
theme_minimal() +
theme(
axis.text.x = element_text(size = 9, angle = 90, hjust = 1)
) +
theme(legend.position = "bottom") +
theme(legend.position = "bottom") +
labs(size = "Adjusted p-value", fill = "log2 FC", y = "Cancer type", x = "Gene")
}perform_vsd <- function(genes) {
tcga_rcd <- list()
for (project in projects) {
rownames(genes) <- genes$gene_id
tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
}
vsd_rcd <- list()
for (project in projects) {
print(project)
print("=============")
dds <- DESeqDataSetFromMatrix(
countData = tcga_rcd[[project]],
colData = samples[[project]],
design = ~type
)
dds <- filter_genes(dds, min_count = 10)
# Perform variance stabilization
dds <- estimateSizeFactors(dds)
nsub <- sum(rowMeans(counts(dds, normalized = TRUE)) > 10)
vsd <- vst(dds, nsub = nsub)
vsd_rcd[[project]] <- assay(vsd)
}
return(vsd_rcd)
}Ferroptosis
Fetch the gene set of interest.
genes <- read.csv(paste0(RCDdb, "Ferroptosis.csv"))
print(genes)genes$gene_id <- cleanid(genes$gene_id)
genes <- distinct(genes, gene_id, .keep_all = TRUE)
genes <- subset(genes, gene_id != "")
genesFilter the genes to include only those in the gene set of interest, and then perform differential gene expression analysis.
deseq.bbl.data.combined <- filter_gene_set_and_perform_dgea(genes)[1] "TCGA-COAD"
[1] "============="Warning: some variables in design formula are characters, converting to factorsestimating size factors
estimating dispersions
gene-wise dispersion estimates
mean-dispersion relationship
final dispersion estimates
fitting model and testing
-- replacing outliers and refitting for 21 genes
-- DESeq argument 'minReplicatesForReplace' = 7
-- original counts are preserved in counts(dds)
estimating dispersions
fitting model and testingdeseq.bbl.data.combinedPlot the results.
plot_dgea(deseq.bbl.data.combined)
Perform variance-stabilizing transformation for further downstream analysis (i.e., for survival analysis).
vsd <- perform_vsd(genes)[1] "TCGA-COAD"
[1] "============="V. Downloading the clinical data
Download clinical data from TCGA, and perform some preprocessing: -
The deceased column should be FALSE if the
patient is alive and TRUE otherwise - The
overall_survival column should reflect the follow-up time
if the patient is alive and the days to death otherwise
download_clinical_data <- function(project) {
clinical_data <- GDCquery_clinic(project)
clinical_data$deceased <- ifelse(clinical_data$vital_status == "Alive", FALSE, TRUE)
clinical_data$overall_survival <- ifelse(clinical_data$vital_status == "Alive",
clinical_data$days_to_last_follow_up,
clinical_data$days_to_death
)
return(clinical_data)
}tcga_clinical <- list()
for (project in projects) {
tcga_clinical[[project]] <- download_clinical_data(project)
}VI. Performing survival analysis
Write utility functions for performing survival analysis.
construct_gene_df <- function(gene_of_interest, project) {
gene_df <- vsd[[project]] %>%
as.data.frame() %>%
rownames_to_column(var = "gene_id") %>%
gather(key = "case_id", value = "counts", -gene_id) %>%
left_join(., genes, by = "gene_id") %>%
dplyr::filter(gene == gene_of_interest) %>%
dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "tumor")))
q1 <- quantile(gene_df$counts, probs = 0.25)
q3 <- quantile(gene_df$counts, probs = 0.75)
gene_df$strata <- ifelse(gene_df$counts >= q3, "HIGH", ifelse(gene_df$counts <= q1, "LOW", "MIDDLE"))
gene_df <- gene_df %>% dplyr::filter(strata %in% c("LOW", "HIGH"))
gene_df$case_id <- paste0(sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 1), '-',
sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 2), '-',
sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 3))
gene_df <- merge(gene_df, tcga_clinical[[project]], by.x = "case_id", by.y = "submitter_id")
return(gene_df)
}compute_surival_fit <- function(gene_df) {
return (survfit(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}compute_cox <- function(gene_df) {
return (coxph(Surv(overall_survival, deceased) ~ strata, data=gene_df))
}plot_survival <- function(fit) {
return(ggsurvplot(fit,
data = gene_df,
pval = T,
risk.table = T,
risk.table.height = 0.3
))
}compute_survival_diff <- function(gene_df) {
return(survdiff(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}Perform survival analysis by testing for the difference in the Kaplan-Meier curves using the G-rho family of Harrington and Fleming tests: https://rdrr.io/cran/survival/man/survdiff.html
significant_projects <- c()
significant_genes <- c()
ctr <- 1
for (project in projects) {
for (gene in c(genes$gene)) {
cat(project, gene, "\n\n")
error <- tryCatch (
{
gene_df <- construct_gene_df(gene, project)
},
error = function(e) {
cat("\n\n============================\n\n")
e
}
)
if(inherits(error, "error")) next
if (nrow(gene_df) > 0) {
fit <- compute_surival_fit(gene_df)
tryCatch (
{
survival <- compute_survival_diff(gene_df)
cox <- compute_cox(gene_df)
print(ctr)
ctr <- ctr + 1
print(survival)
cat("\n")
print(cox)
print(plot_survival(fit))
if (pchisq(survival$chisq, length(survival$n)-1, lower.tail = FALSE) < 0.05) {
significant_projects <- c(significant_projects, project)
significant_genes <- c(significant_genes, gene)
}
},
error = function(e) {
}
)
}
cat("\n\n============================\n\n")
}
}TCGA-COAD MIR212
============================
TCGA-COAD NR5A2
[1] 1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.8 1.16 2.24
strata=LOW 12 5 3.2 1.01 2.24
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.511 4.532 1.103 1.37 0.171
Likelihood ratio test=2.47 on 1 df, p=0.1161
n= 24, number of events= 6
============================
TCGA-COAD TFAM
[1] 2
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.29 1.288 2.3
strata=LOW 12 3 1.71 0.969 2.3
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.100e+01 1.312e+09 2.372e+04 0.001 0.999
Likelihood ratio test=3.41 on 1 df, p=0.06482
n= 24, number of events= 3
============================
TCGA-COAD CREB5
[1] 3
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.41 0.828 2.1
strata=LOW 12 3 1.59 1.260 2.1
Chisq= 2.1 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.525 4.593 1.157 1.318 0.187
Likelihood ratio test=2.07 on 1 df, p=0.1502
n= 24, number of events= 4
============================
TCGA-COAD NOS2
[1] 4
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.3 0.514 1.87
strata=LOW 12 3 1.7 1.001 1.87
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.532 4.626 1.205 1.271 0.204
Likelihood ratio test=1.9 on 1 df, p=0.1676
n= 24, number of events= 5
============================
TCGA-COAD HULC
[1] 5
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.95 0.308 0.77
strata=LOW 12 4 3.05 0.299 0.77
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7909 2.2053 0.9235 0.856 0.392
Likelihood ratio test=0.75 on 1 df, p=0.3853
n= 24, number of events= 6
============================
TCGA-COAD PLXNB2
[1] 6
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 0.722 0.1068 0.168
strata=LOW 12 1 1.278 0.0604 0.168
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5726 0.5641 1.4168 -0.404 0.686
Likelihood ratio test=0.16 on 1 df, p=0.6881
n= 24, number of events= 2
============================
TCGA-COAD KIF20A
[1] 7
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.78 0.161 0.619
strata=LOW 12 3 2.22 0.273 0.619
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8821 2.4160 1.1576 0.762 0.446
Likelihood ratio test=0.66 on 1 df, p=0.4179
n= 24, number of events= 6
============================
TCGA-COAD TIMP1
[1] 8
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 2.38 5.51 9.2
strata=LOW 12 0 3.62 3.62 9.2
Chisq= 9.2 on 1 degrees of freedom, p= 0.002
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.173e+01 3.653e-10 1.714e+04 -0.001 0.999
Likelihood ratio test=11.17 on 1 df, p=0.0008311
n= 24, number of events= 6
============================
TCGA-COAD MIR615
============================
TCGA-COAD MIR93
============================
TCGA-COAD ENO3
[1] 9
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.59 0.0458 0.112
strata=LOW 12 3 3.41 0.0484 0.112
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2726 0.7614 0.8170 -0.334 0.739
Likelihood ratio test=0.11 on 1 df, p=0.739
n= 24, number of events= 7
============================
TCGA-COAD MMD
[1] 10
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 5.62 1.22 4.44
strata=LOW 12 5 2.38 2.89 4.44
Chisq= 4.4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.6070 4.9877 0.8434 1.905 0.0567
Likelihood ratio test=4.15 on 1 df, p=0.04173
n= 24, number of events= 8
============================
TCGA-COAD NQO1
[1] 11
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.2 0.447 1.24
strata=LOW 12 3 1.8 0.792 1.24
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9779 2.6589 0.9134 1.071 0.284
Likelihood ratio test=1.18 on 1 df, p=0.2781
n= 24, number of events= 5
============================
TCGA-COAD MARCHF5
[1] 12
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.52 0.0912 0.184
strata=LOW 12 3 3.48 0.0661 0.184
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3900 0.6771 0.9140 -0.427 0.67
Likelihood ratio test=0.19 on 1 df, p=0.6665
n= 24, number of events= 6
============================
TCGA-COAD JUN
[1] 13
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.95 0.000567 0.00152
strata=LOW 12 4 4.05 0.000692 0.00152
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.02881 0.97160 0.73891 -0.039 0.969
Likelihood ratio test=0 on 1 df, p=0.9689
n= 24, number of events= 9
============================
TCGA-COAD ALDH3A2
[1] 14
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.39 0.0853 0.193
strata=LOW 12 4 4.61 0.0812 0.193
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3112 0.7326 0.7104 -0.438 0.661
Likelihood ratio test=0.19 on 1 df, p=0.662
n= 24, number of events= 9
============================
TCGA-COAD ALOX5
[1] 15
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 3.94 1.07 3.65
strata=LOW 12 0 2.06 2.06 3.65
Chisq= 3.7 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.099e+01 7.682e-10 1.867e+04 -0.001 0.999
Likelihood ratio test=5.44 on 1 df, p=0.01965
n= 24, number of events= 6
============================
TCGA-COAD PARP9
[1] 16
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.44 0.0573 0.158
strata=LOW 12 3 2.56 0.0772 0.158
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3611 1.4350 0.9132 0.395 0.692
Likelihood ratio test=0.16 on 1 df, p=0.6897
n= 24, number of events= 6
============================
TCGA-COAD GLRX5
[1] 17
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 0.775 0.0653 0.107
strata=LOW 12 1 1.225 0.0413 0.107
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4581 0.6325 1.4147 -0.324 0.746
Likelihood ratio test=0.1 on 1 df, p=0.7471
n= 24, number of events= 2
============================
TCGA-COAD METTL14
[1] 18
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.52 0.92 3.3
strata=LOW 12 3 1.48 1.57 3.3
Chisq= 3.3 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.139e+01 1.948e+09 2.378e+04 0.001 0.999
Likelihood ratio test=4.43 on 1 df, p=0.03532
n= 24, number of events= 4
============================
TCGA-COAD TOR2A
[1] 19
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.1 0.388 0.67
strata=LOW 12 2 2.9 0.280 0.67
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7322 0.4808 0.9142 -0.801 0.423
Likelihood ratio test=0.66 on 1 df, p=0.4169
n= 24, number of events= 5
============================
TCGA-COAD PARP14
[1] 20
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.62 0.723 2.14
strata=LOW 12 4 2.38 1.096 2.14
Chisq= 2.1 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.512 4.535 1.128 1.34 0.18
Likelihood ratio test=2.27 on 1 df, p=0.1321
n= 24, number of events= 6
============================
TCGA-COAD MIR130B
============================
TCGA-COAD CERS6-AS1
============================
TCGA-COAD NFS1
[1] 21
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.93 0.00267 0.00517
strata=LOW 12 3 3.07 0.00168 0.00517
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07191 0.93062 1.00074 -0.072 0.943
Likelihood ratio test=0.01 on 1 df, p=0.9427
n= 24, number of events= 5
============================
TCGA-COAD SLC3A2
[1] 22
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 0.529 0.418 0.889
strata=LOW 12 1 1.471 0.151 0.889
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.109e+01 6.926e-10 4.030e+04 -0.001 1
Likelihood ratio test=1.27 on 1 df, p=0.2594
n= 24, number of events= 2
============================
TCGA-COAD ZFAS1
[1] 23
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.06 0.001102 0.00225
strata=LOW 12 4 3.94 0.000855 0.00225
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.03881 1.03957 0.81753 0.047 0.962
Likelihood ratio test=0 on 1 df, p=0.9621
n= 24, number of events= 7
============================
TCGA-COAD PANX1
[1] 24
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.39 0.0341 0.156
strata=LOW 12 2 1.61 0.0928 0.156
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3927 1.4810 1.0012 0.392 0.695
Likelihood ratio test=0.15 on 1 df, p=0.6958
n= 24, number of events= 6
============================
TCGA-COAD HSPB1
[1] 25
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.18 1.041 2.31
strata=LOW 12 2 3.82 0.867 2.31
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5343 0.2156 1.1048 -1.389 0.165
Likelihood ratio test=2.54 on 1 df, p=0.1111
n= 24, number of events= 7
============================
TCGA-COAD CREB1
[1] 26
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.79 1.15 3.36
strata=LOW 12 4 2.21 1.45 3.36
Chisq= 3.4 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.110e+01 1.456e+09 2.051e+04 0.001 0.999
Likelihood ratio test=4.87 on 1 df, p=0.02737
n= 24, number of events= 5
============================
TCGA-COAD EZH2
[1] 27
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.48 0.63 2.38
strata=LOW 12 3 1.52 1.44 2.38
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.620 5.054 1.163 1.393 0.164
Likelihood ratio test=2.31 on 1 df, p=0.1283
n= 24, number of events= 5
============================
TCGA-COAD SLC40A1
[1] 28
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.79 0.846 2.31
strata=LOW 12 5 3.21 1.000 2.31
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2416 3.4612 0.8687 1.429 0.153
Likelihood ratio test=2.21 on 1 df, p=0.1373
n= 24, number of events= 7
============================
TCGA-COAD PAQR3
[1] 29
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.47 0.0646 0.18
strata=LOW 12 3 2.53 0.0888 0.18
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3846 1.4690 0.9131 0.421 0.674
Likelihood ratio test=0.18 on 1 df, p=0.6706
n= 24, number of events= 6
============================
TCGA-COAD MIR545
============================
TCGA-COAD MIR6077
============================
TCGA-COAD MIR424
============================
TCGA-COAD NOX5
[1] 30
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.63 0.0515 0.109
strata=LOW 12 2 2.37 0.0572 0.109
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3019 0.7394 0.9159 -0.33 0.742
Likelihood ratio test=0.11 on 1 df, p=0.7397
n= 24, number of events= 5
============================
TCGA-COAD DHODH
[1] 31
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.12 0.251 0.466
strata=LOW 12 3 3.88 0.202 0.466
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5244 0.5919 0.7764 -0.675 0.499
Likelihood ratio test=0.46 on 1 df, p=0.4962
n= 24, number of events= 7
============================
TCGA-COAD PTPN18
[1] 32
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.87 0.00592 0.0115
strata=LOW 12 3 3.13 0.00543 0.0115
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.08821 0.91557 0.82236 -0.107 0.915
Likelihood ratio test=0.01 on 1 df, p=0.9146
n= 24, number of events= 6
============================
TCGA-COAD IARS1
[1] 33
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.09 0.00187 0.00455
strata=LOW 12 3 2.91 0.00263 0.00455
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05177 1.05314 0.76775 0.067 0.946
Likelihood ratio test=0 on 1 df, p=0.9463
n= 24, number of events= 7
============================
TCGA-COAD IL4R
[1] 34
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.21 0.192 0.502
strata=LOW 12 2 2.79 0.222 0.502
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6368 0.5290 0.9140 -0.697 0.486
Likelihood ratio test=0.5 on 1 df, p=0.4803
n= 24, number of events= 6
============================
TCGA-COAD SENP1
[1] 35
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.78 0.345 0.853
strata=LOW 12 2 1.22 0.507 0.853
Chisq= 0.9 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.080 2.944 1.226 0.881 0.379
Likelihood ratio test=0.84 on 1 df, p=0.3606
n= 24, number of events= 3
============================
TCGA-COAD IFNA16
============================
TCGA-COAD SOX2
[1] 36
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.93 0.589 0.962
strata=LOW 12 3 4.07 0.280 0.962
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8687 0.4195 0.9136 -0.951 0.342
Likelihood ratio test=0.93 on 1 df, p=0.3352
n= 24, number of events= 6
============================
TCGA-COAD LIFR
[1] 37
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.11 0.00414 0.00865
strata=LOW 12 4 3.89 0.00332 0.00865
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07613 1.07910 0.81855 0.093 0.926
Likelihood ratio test=0.01 on 1 df, p=0.9259
n= 24, number of events= 7
============================
TCGA-COAD MIR199A2
============================
TCGA-COAD COX4I2
[1] 38
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.52 0.872 2.34
strata=LOW 12 1 2.48 0.885 2.34
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5967 0.2026 1.1567 -1.38 0.167
Likelihood ratio test=2.28 on 1 df, p=0.1312
n= 24, number of events= 5
============================
TCGA-COAD ATF2
[1] 39
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.53 0.183 0.374
strata=LOW 12 3 2.47 0.113 0.374
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7329 2.0811 1.2252 0.598 0.55
Likelihood ratio test=0.38 on 1 df, p=0.5374
n= 24, number of events= 4
============================
TCGA-COAD ABCC5
[1] 40
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.46 0.0861 0.187
strata=LOW 12 4 3.54 0.0599 0.187
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4106 1.5077 0.9546 0.43 0.667
Likelihood ratio test=0.19 on 1 df, p=0.6646
n= 24, number of events= 6
============================
TCGA-COAD CCDC6
[1] 41
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.97 0.781 2.32
strata=LOW 12 5 3.03 1.282 2.32
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2124 3.3615 0.8437 1.437 0.151
Likelihood ratio test=2.32 on 1 df, p=0.1277
n= 24, number of events= 8
============================
TCGA-COAD OTUB1
[1] 42
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.63 0.0864 0.189
strata=LOW 12 1 1.37 0.1022 0.189
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5262 0.5908 1.2252 -0.429 0.668
Likelihood ratio test=0.19 on 1 df, p=0.66
n= 24, number of events= 3
============================
TCGA-COAD ALOXE3
[1] 43
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.77 0.0109 0.0265
strata=LOW 12 4 4.23 0.0123 0.0265
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1161 0.8904 0.7138 -0.163 0.871
Likelihood ratio test=0.03 on 1 df, p=0.8708
n= 24, number of events= 9
============================
TCGA-COAD SCP2
[1] 44
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.65 0.114 0.565
strata=LOW 12 2 1.35 0.308 0.565
Chisq= 0.6 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8936 2.4440 1.2285 0.727 0.467
Likelihood ratio test=0.57 on 1 df, p=0.4516
n= 24, number of events= 5
============================
TCGA-COAD PHKG2
[1] 45
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.95 0.000939 0.0019
strata=LOW 12 3 3.05 0.000906 0.0019
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.0362 0.9644 0.8296 -0.044 0.965
Likelihood ratio test=0 on 1 df, p=0.9652
n= 24, number of events= 6
============================
TCGA-COAD MTDH
[1] 46
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.6 0.137 0.296
strata=LOW 12 4 3.4 0.105 0.296
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5006 1.6497 0.9286 0.539 0.59
Likelihood ratio test=0.3 on 1 df, p=0.5857
n= 24, number of events= 6
============================
TCGA-COAD ACO1
[1] 47
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 0.9 0.01111 0.0204
strata=LOW 12 2 2.1 0.00476 0.0204
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2027 0.8165 1.4215 -0.143 0.887
Likelihood ratio test=0.02 on 1 df, p=0.8867
n= 24, number of events= 3
============================
TCGA-COAD MIR137
============================
TCGA-COAD OIP5-AS1
[1] 48
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.87 0.00837 0.0158
strata=LOW 12 3 3.13 0.00502 0.0158
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1257 0.8819 1.0010 -0.126 0.9
Likelihood ratio test=0.02 on 1 df, p=0.9001
n= 24, number of events= 5
============================
TCGA-COAD MIR494
============================
TCGA-COAD MLLT1
[1] 49
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3 7.57e-06 1.6e-05
strata=LOW 12 3 3 7.55e-06 1.6e-05
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.003356 0.996649 0.839511 -0.004 0.997
Likelihood ratio test=0 on 1 df, p=0.9968
n= 24, number of events= 6
============================
TCGA-COAD MIR19B1
============================
TCGA-COAD RPTOR
[1] 50
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.25 0.251 0.471
strata=LOW 12 2 2.75 0.205 0.471
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6268 0.5343 0.9265 -0.676 0.499
Likelihood ratio test=0.47 on 1 df, p=0.4935
n= 24, number of events= 5
============================
TCGA-COAD GCH1
[1] 51
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.68 0.0223 0.0842
strata=LOW 12 2 2.32 0.0449 0.0842
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2647 0.7674 0.9149 -0.289 0.772
Likelihood ratio test=0.08 on 1 df, p=0.7707
n= 24, number of events= 7
============================
TCGA-COAD PARP16
[1] 52
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.78 0.661 2.32
strata=LOW 12 4 2.22 1.421 2.32
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2661 3.5471 0.8824 1.435 0.151
Likelihood ratio test=2.23 on 1 df, p=0.1355
n= 24, number of events= 7
============================
TCGA-COAD MIR9-3
============================
TCGA-COAD CISD3
[1] 53
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.63 0.0527 0.0942
strata=LOW 12 3 3.37 0.0411 0.0942
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2505 0.7784 0.8182 -0.306 0.76
Likelihood ratio test=0.09 on 1 df, p=0.7598
n= 24, number of events= 6
============================
TCGA-COAD USP35
[1] 54
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.3 0.0392 0.0759
strata=LOW 12 4 3.7 0.0243 0.0759
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2561 1.2919 0.9317 0.275 0.783
Likelihood ratio test=0.08 on 1 df, p=0.7821
n= 24, number of events= 6
============================
TCGA-COAD PRKAA1
[1] 55
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.09 0.57 1.2
strata=LOW 12 4 2.91 0.41 1.2
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.194 3.299 1.156 1.033 0.302
Likelihood ratio test=1.24 on 1 df, p=0.2651
n= 24, number of events= 5
============================
TCGA-COAD MAPK14
[1] 56
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.83 1.83 3.45
strata=LOW 12 5 3.17 1.05 3.45
Chisq= 3.5 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.110e+01 1.459e+09 2.039e+04 0.001 0.999
Likelihood ratio test=4.96 on 1 df, p=0.02587
n= 24, number of events= 5
============================
TCGA-COAD GRIA3
[1] 57
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.74 0.0177 0.0381
strata=LOW 12 3 3.26 0.0203 0.0381
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1492 0.8614 0.7649 -0.195 0.845
Likelihood ratio test=0.04 on 1 df, p=0.8448
n= 24, number of events= 7
============================
TCGA-COAD KDM5C
[1] 58
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.37 0.560 1.13
strata=LOW 12 6 4.63 0.408 1.13
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8771 2.4039 0.8501 1.032 0.302
Likelihood ratio test=1.17 on 1 df, p=0.2799
n= 24, number of events= 8
============================
TCGA-COAD DECR1
[1] 59
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.36 0.121 0.281
strata=LOW 12 2 2.64 0.155 0.281
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4583 0.6323 0.8723 -0.525 0.599
Likelihood ratio test=0.29 on 1 df, p=0.5916
n= 24, number of events= 6
============================
TCGA-COAD VCP
[1] 60
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.3 0.21 0.403
strata=LOW 12 2 2.7 0.18 0.403
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5817 0.5590 0.9276 -0.627 0.531
Likelihood ratio test=0.4 on 1 df, p=0.5257
n= 24, number of events= 5
============================
TCGA-COAD MIR129-1
============================
TCGA-COAD PARP10
[1] 61
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.021 0.000147 0.000916
strata=LOW 12 1 0.979 0.000453 0.000916
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.04351 1.04447 1.43744 0.03 0.976
Likelihood ratio test=0 on 1 df, p=0.9759
n= 24, number of events= 4
============================
TCGA-COAD ULK2
[1] 62
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.14 0.01823 0.0306
strata=LOW 12 3 2.86 0.00731 0.0306
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2175 1.2430 1.2458 0.175 0.861
Likelihood ratio test=0.03 on 1 df, p=0.86
n= 24, number of events= 4
============================
TCGA-COAD CISD1
[1] 63
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.86 0.395 0.751
strata=LOW 12 3 2.14 0.342 0.751
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9706 2.6395 1.1628 0.835 0.404
Likelihood ratio test=0.79 on 1 df, p=0.3732
n= 24, number of events= 4
============================
TCGA-COAD MIR147A
============================
TCGA-COAD BBOX1-AS1
[1] 64
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.89 0.00328 0.00745
strata=LOW 12 3 3.11 0.00410 0.00745
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.06623 0.93592 0.76737 -0.086 0.931
Likelihood ratio test=0.01 on 1 df, p=0.9311
n= 24, number of events= 7
============================
TCGA-COAD RB1
[1] 65
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.79 0.349 0.865
strata=LOW 12 3 2.21 0.282 0.865
Chisq= 0.9 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.086 2.961 1.225 0.886 0.376
Likelihood ratio test=0.85 on 1 df, p=0.3576
n= 24, number of events= 4
============================
TCGA-COAD TTPA
[1] 66
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.88 0.410 0.688
strata=LOW 12 5 4.12 0.187 0.688
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9114 2.4879 1.1340 0.804 0.422
Likelihood ratio test=0.75 on 1 df, p=0.3859
n= 24, number of events= 6
============================
TCGA-COAD CDC25A
[1] 67
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.56 0.0769 0.28
strata=LOW 12 1 1.44 0.1362 0.28
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6564 0.5187 1.2600 -0.521 0.602
Likelihood ratio test=0.29 on 1 df, p=0.593
n= 24, number of events= 4
============================
TCGA-COAD PCAT1
[1] 68
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 3.17 1.49 4.11
strata=LOW 12 5 2.83 1.67 4.11
Chisq= 4.1 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.956 7.074 1.122 1.744 0.0812
Likelihood ratio test=4 on 1 df, p=0.04557
n= 24, number of events= 6
============================
TCGA-COAD DAZAP1
[1] 69
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.42 0.0406 0.24
strata=LOW 12 2 1.58 0.1139 0.24
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5923 1.8081 1.2257 0.483 0.629
Likelihood ratio test=0.25 on 1 df, p=0.6198
n= 24, number of events= 6
============================
TCGA-COAD PEX2
[1] 70
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.25 0.249 0.46
strata=LOW 12 3 3.75 0.149 0.46
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6149 0.5407 0.9205 -0.668 0.504
Likelihood ratio test=0.46 on 1 df, p=0.4986
n= 24, number of events= 6
============================
TCGA-COAD MIR124-3
============================
TCGA-COAD TRIM21
[1] 71
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.04 0.267 0.74
strata=LOW 12 4 2.96 0.364 0.74
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7380 2.0918 0.8761 0.842 0.4
Likelihood ratio test=0.75 on 1 df, p=0.3858
n= 24, number of events= 7
============================
TCGA-COAD MEG3
[1] 72
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.35 0.179 0.341
strata=LOW 12 3 3.65 0.115 0.341
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5288 0.5893 0.9160 -0.577 0.564
Likelihood ratio test=0.34 on 1 df, p=0.5591
n= 24, number of events= 6
============================
TCGA-COAD GCLC
[1] 73
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.118 0.59 2.54
strata=LOW 12 2 0.882 1.42 2.54
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.146e+01 2.099e+09 2.877e+04 0.001 0.999
Likelihood ratio test=3.28 on 1 df, p=0.07033
n= 24, number of events= 3
============================
TCGA-COAD IDH2
[1] 74
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.94 0.952 3.83
strata=LOW 12 4 2.06 1.816 3.83
Chisq= 3.8 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.119e+01 1.602e+09 2.022e+04 0.001 0.999
Likelihood ratio test=5.37 on 1 df, p=0.02045
n= 24, number of events= 6
============================
TCGA-COAD FNDC5
[1] 75
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.1 0.00292 0.00624
strata=LOW 12 4 3.9 0.00231 0.00624
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.06562 1.06782 0.83080 0.079 0.937
Likelihood ratio test=0.01 on 1 df, p=0.9371
n= 24, number of events= 7
============================
TCGA-COAD FANCD2
[1] 76
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.144 0.61 2.67
strata=LOW 12 2 0.856 1.53 2.67
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.153e+01 2.248e+09 2.897e+04 0.001 0.999
Likelihood ratio test=3.4 on 1 df, p=0.06534
n= 24, number of events= 3
============================
TCGA-COAD LCN2
[1] 77
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.03 0.309 0.659
strata=LOW 12 2 2.97 0.316 0.659
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7034 0.4949 0.8826 -0.797 0.425
Likelihood ratio test=0.67 on 1 df, p=0.4132
n= 24, number of events= 6
============================
TCGA-COAD TFR2
[1] 78
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.36 0.0395 0.117
strata=LOW 12 3 2.64 0.0504 0.117
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3265 1.3861 0.9587 0.341 0.733
Likelihood ratio test=0.12 on 1 df, p=0.7311
n= 24, number of events= 6
============================
TCGA-COAD PARP12
[1] 79
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.32 0.522 1.4
strata=LOW 12 4 2.68 0.645 1.4
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.247 3.479 1.121 1.112 0.266
Likelihood ratio test=1.52 on 1 df, p=0.2173
n= 24, number of events= 6
============================
TCGA-COAD NR1D1
[1] 80
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.91 0.302 0.788
strata=LOW 12 2 3.09 0.382 0.788
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7515 0.4717 0.8664 -0.867 0.386
Likelihood ratio test=0.8 on 1 df, p=0.3709
n= 24, number of events= 7
============================
TCGA-COAD ATG13
[1] 81
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.82 0.0183 0.0469
strata=LOW 12 1 1.18 0.0282 0.0469
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2656 0.7668 1.2294 -0.216 0.829
Likelihood ratio test=0.05 on 1 df, p=0.8267
n= 24, number of events= 3
============================
TCGA-COAD TMSB4X
[1] 82
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.78 0.0278 0.0696
strata=LOW 12 1 1.22 0.0404 0.0696
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3247 0.7227 1.2363 -0.263 0.793
Likelihood ratio test=0.07 on 1 df, p=0.7896
n= 24, number of events= 3
============================
TCGA-COAD CDK14
[1] 83
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.2 0.287 0.645
strata=LOW 12 1 1.8 0.353 0.645
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9003 0.4064 1.1583 -0.777 0.437
Likelihood ratio test=0.68 on 1 df, p=0.4083
n= 24, number of events= 4
============================
TCGA-COAD RP1-228H13.5
[1] 84
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.25 0.368 1.07
strata=LOW 12 4 2.75 0.568 1.07
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8785 2.4072 0.8746 1.004 0.315
Likelihood ratio test=1.08 on 1 df, p=0.2991
n= 24, number of events= 7
============================
TCGA-COAD NOX3
============================
TCGA-COAD IFNA17
============================
TCGA-COAD ALOX12B
[1] 85
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.94 0.576 0.889
strata=LOW 12 3 4.06 0.276 0.889
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7715 0.4623 0.8362 -0.923 0.356
Likelihood ratio test=0.83 on 1 df, p=0.3614
n= 24, number of events= 6
============================
TCGA-COAD PGRMC1
[1] 86
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.45 0.470 1.9
strata=LOW 12 4 2.55 0.819 1.9
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.1137 3.0455 0.8454 1.317 0.188
Likelihood ratio test=1.67 on 1 df, p=0.1958
n= 24, number of events= 7
============================
TCGA-COAD ULK1
[1] 87
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.89 0.646 1.25
strata=LOW 12 1 2.11 0.581 1.25
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2270 0.2932 1.1626 -1.055 0.291
Likelihood ratio test=1.3 on 1 df, p=0.2551
n= 24, number of events= 4
============================
TCGA-COAD TRIM26
[1] 88
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.33 0.0320 0.117
strata=LOW 12 2 1.67 0.0636 0.117
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3544 1.4253 1.0400 0.341 0.733
Likelihood ratio test=0.12 on 1 df, p=0.7335
n= 24, number of events= 5
============================
TCGA-COAD QSOX1
[1] 89
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.12 0.00426 0.00911
strata=LOW 12 3 2.88 0.00460 0.00911
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07898 1.08219 0.82784 0.095 0.924
Likelihood ratio test=0.01 on 1 df, p=0.924
n= 24, number of events= 6
============================
TCGA-COAD ATM
[1] 90
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.28 0.498 0.967
strata=LOW 12 5 3.72 0.438 0.967
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8106 2.2492 0.8456 0.959 0.338
Likelihood ratio test=1 on 1 df, p=0.3166
n= 24, number of events= 7
============================
TCGA-COAD MIB2
[1] 91
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.85 0.468 0.933
strata=LOW 12 2 3.15 0.422 0.933
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8303 0.4359 0.8818 -0.942 0.346
Likelihood ratio test=0.94 on 1 df, p=0.3318
n= 24, number of events= 6
============================
TCGA-COAD SLC1A5
[1] 92
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 2.73 1.88 3.55
strata=LOW 12 2 4.27 1.20 3.55
Chisq= 3.5 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.8284 0.1607 1.1034 -1.657 0.0975
Likelihood ratio test=3.76 on 1 df, p=0.05234
n= 24, number of events= 7
============================
TCGA-COAD MIR2115
============================
TCGA-COAD LINC00336
[1] 93
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.66 0.488 1.47
strata=LOW 12 1 2.34 0.765 1.47
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2755 0.2793 1.1240 -1.135 0.256
Likelihood ratio test=1.58 on 1 df, p=0.2081
n= 24, number of events= 6
============================
TCGA-COAD NDRG1
[1] 94
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.41 0.103 0.25
strata=LOW 12 2 2.59 0.135 0.25
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4387 0.6449 0.8845 -0.496 0.62
Likelihood ratio test=0.26 on 1 df, p=0.6133
n= 24, number of events= 6
============================
TCGA-COAD TAFAZZIN
[1] 95
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.37 0.0404 0.149
strata=LOW 12 2 1.63 0.0835 0.149
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3943 1.4834 1.0286 0.383 0.701
Likelihood ratio test=0.15 on 1 df, p=0.7021
n= 24, number of events= 5
============================
TCGA-COAD MIR135B
============================
TCGA-COAD GLS2
[1] 96
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.33 0.1335 0.234
strata=LOW 12 5 5.67 0.0785 0.234
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3442 0.7088 0.7154 -0.481 0.63
Likelihood ratio test=0.23 on 1 df, p=0.6311
n= 24, number of events= 9
============================
TCGA-COAD HELLS
[1] 97
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.73 0.802 4.09
strata=LOW 12 3 1.27 2.352 4.09
Chisq= 4.1 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.156e+01 2.305e+09 2.372e+04 0.001 0.999
Likelihood ratio test=5.16 on 1 df, p=0.02312
n= 24, number of events= 5
============================
TCGA-COAD KLF2
[1] 98
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.72 0.606 1.76
strata=LOW 12 1 2.28 0.721 1.76
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4562 0.2331 1.1827 -1.231 0.218
Likelihood ratio test=1.79 on 1 df, p=0.1814
n= 24, number of events= 5
============================
TCGA-COAD TFAP2A
[1] 99
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.09 0.00284 0.0129
strata=LOW 12 2 1.91 0.00461 0.0129
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1402 1.1505 1.2356 0.113 0.91
Likelihood ratio test=0.01 on 1 df, p=0.909
n= 24, number of events= 5
============================
TCGA-COAD FURIN
[1] 100
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.08 0.00525 0.00821
strata=LOW 12 2 1.92 0.00294 0.00821
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.111 1.117 1.226 0.091 0.928
Likelihood ratio test=0.01 on 1 df, p=0.9274
n= 24, number of events= 3
============================
TCGA-COAD CDH1
[1] 101
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.07 0.555 1.19
strata=LOW 12 5 3.93 0.293 1.19
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.203 3.331 1.167 1.031 0.302
Likelihood ratio test=1.23 on 1 df, p=0.267
n= 24, number of events= 6
============================
TCGA-COAD MIR6852
============================
TCGA-COAD MIR670
============================
TCGA-COAD TYRO3
[1] 102
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.11 0.586 1.81
strata=LOW 12 3 1.89 0.657 1.81
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.082e+01 1.097e+09 2.452e+04 0.001 0.999
Likelihood ratio test=2.82 on 1 df, p=0.09325
n= 24, number of events= 4
============================
TCGA-COAD MIR4715
============================
TCGA-COAD ABHD12
[1] 103
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.46 0.198 0.388
strata=LOW 12 2 2.54 0.114 0.388
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7476 0.4735 1.2277 -0.609 0.543
Likelihood ratio test=0.39 on 1 df, p=0.53
n= 24, number of events= 4
============================
TCGA-COAD ATG7
[1] 104
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.57 0.537 1.72
strata=LOW 12 4 2.43 1.007 1.72
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0887 2.9704 0.8712 1.25 0.211
Likelihood ratio test=1.68 on 1 df, p=0.1947
n= 24, number of events= 7
============================
TCGA-COAD MT1G
[1] 105
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.49 0.159 0.252
strata=LOW 12 4 3.51 0.067 0.252
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5724 1.7725 1.1550 0.496 0.62
Likelihood ratio test=0.27 on 1 df, p=0.6049
n= 24, number of events= 5
============================
TCGA-COAD SAT1
[1] 106
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.92 0.00303 0.0085
strata=LOW 12 3 3.08 0.00190 0.0085
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1131 0.8931 1.2276 -0.092 0.927
Likelihood ratio test=0.01 on 1 df, p=0.9262
n= 24, number of events= 5
============================
TCGA-COAD MIR182
============================
TCGA-COAD HOTAIR
[1] 107
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 5.57 0.443 1.47
strata=LOW 16 5 3.43 0.720 1.47
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0042 2.7299 0.8578 1.171 0.242
Likelihood ratio test=1.52 on 1 df, p=0.2172
n= 28, number of events= 9
============================
TCGA-COAD PIR
[1] 108
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.17 0.318 0.705
strata=LOW 12 2 2.83 0.244 0.705
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9403 0.3905 1.1602 -0.81 0.418
Likelihood ratio test=0.75 on 1 df, p=0.3879
n= 24, number of events= 5
============================
TCGA-COAD ELAVL1
[1] 109
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.62 0.0836 0.311
strata=LOW 12 3 2.38 0.1623 0.311
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5053 1.6576 0.9152 0.552 0.581
Likelihood ratio test=0.31 on 1 df, p=0.5764
n= 24, number of events= 7
============================
TCGA-COAD ACADSB
[1] 110
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.53 0.925 3.12
strata=LOW 12 3 1.47 1.591 3.12
Chisq= 3.1 on 1 degrees of freedom, p= 0.08
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.124e+01 1.685e+09 2.322e+04 0.001 0.999
Likelihood ratio test=4.28 on 1 df, p=0.03856
n= 24, number of events= 4
============================
TCGA-COAD NCOA4
[1] 111
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.36 1.359 2.48
strata=LOW 12 4 2.64 0.699 2.48
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.103e+01 1.358e+09 2.337e+04 0.001 0.999
Likelihood ratio test=3.62 on 1 df, p=0.05708
n= 24, number of events= 4
============================
TCGA-COAD IFNA10
============================
TCGA-COAD IFNA13
============================
TCGA-COAD MIR9-2
============================
TCGA-COAD RRM2
[1] 112
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.04 0.266 0.716
strata=LOW 12 4 2.96 0.362 0.716
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7180 2.0504 0.8666 0.829 0.407
Likelihood ratio test=0.73 on 1 df, p=0.3931
n= 24, number of events= 7
============================
TCGA-COAD EPSTI1
[1] 113
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.93 0.174 0.51
strata=LOW 12 4 3.07 0.279 0.51
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5478 1.7294 0.7756 0.706 0.48
Likelihood ratio test=0.51 on 1 df, p=0.4767
n= 24, number of events= 8
============================
TCGA-COAD LINC00551
[1] 114
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.29 0.0358 0.0697
strata=LOW 12 3 2.71 0.0302 0.0697
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2471 1.2804 0.9384 0.263 0.792
Likelihood ratio test=0.07 on 1 df, p=0.7909
n= 24, number of events= 5
============================
TCGA-COAD SLC25A28
[1] 115
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.33 0.191 0.601
strata=LOW 12 1 1.67 0.267 0.601
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9171 0.3997 1.2250 -0.749 0.454
Likelihood ratio test=0.6 on 1 df, p=0.4382
n= 24, number of events= 4
============================
TCGA-COAD LINC00973
============================
TCGA-COAD MIR378A
============================
TCGA-COAD MGST1
[1] 116
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.26 0.924 1.8
strata=LOW 12 2 3.74 0.807 1.8
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0899 0.3363 0.8486 -1.284 0.199
Likelihood ratio test=1.83 on 1 df, p=0.1756
n= 24, number of events= 7
============================
TCGA-COAD MIB1
[1] 117
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2 3.14e-06 6.29e-06
strata=LOW 12 3 3 2.09e-06 6.29e-06
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.002509 0.997494 1.000630 -0.003 0.998
Likelihood ratio test=0 on 1 df, p=0.998
n= 24, number of events= 5
============================
TCGA-COAD SRC
[1] 118
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.58 1.28 2.19
strata=LOW 12 2 3.42 0.59 2.19
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5874 0.2045 1.1749 -1.351 0.177
Likelihood ratio test=2.17 on 1 df, p=0.141
n= 24, number of events= 5
============================
TCGA-COAD ATG5
[1] 119
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.77 1.77 4.32
strata=LOW 12 4 2.23 1.40 4.32
Chisq= 4.3 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.164e+01 2.491e+09 2.394e+04 0.001 0.999
Likelihood ratio test=5.36 on 1 df, p=0.02063
n= 24, number of events= 4
============================
TCGA-COAD ACVR1B
[1] 120
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.84 0.00846 0.0162
strata=LOW 12 4 4.16 0.00579 0.0162
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1041 0.9012 0.8188 -0.127 0.899
Likelihood ratio test=0.02 on 1 df, p=0.8989
n= 24, number of events= 7
============================
TCGA-COAD NT5DC2
[1] 121
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.63 0.0510 0.139
strata=LOW 12 2 2.37 0.0567 0.139
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3715 0.6897 1.0012 -0.371 0.711
Likelihood ratio test=0.14 on 1 df, p=0.7114
n= 24, number of events= 5
============================
TCGA-COAD PIK3CA
[1] 122
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.45 0.0824 0.213
strata=LOW 12 2 1.55 0.1302 0.213
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4576 1.5803 1.0005 0.457 0.647
Likelihood ratio test=0.21 on 1 df, p=0.6488
n= 24, number of events= 4
============================
TCGA-COAD NUPR1
[1] 123
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.19 0.297 0.67
strata=LOW 12 2 2.81 0.232 0.67
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9201 0.3985 1.1622 -0.792 0.429
Likelihood ratio test=0.71 on 1 df, p=0.3997
n= 24, number of events= 5
============================
TCGA-COAD AKT1S1
[1] 124
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.75 0.565 1.58
strata=LOW 12 1 2.25 0.692 1.58
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3507 0.2591 1.1559 -1.169 0.243
Likelihood ratio test=1.61 on 1 df, p=0.2045
n= 24, number of events= 5
============================
TCGA-COAD MIR19A
============================
TCGA-COAD USP7
[1] 125
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.82 0.176 0.403
strata=LOW 12 5 4.18 0.160 0.403
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4893 1.6311 0.7780 0.629 0.529
Likelihood ratio test=0.4 on 1 df, p=0.5271
n= 24, number of events= 8
============================
TCGA-COAD TMSB4Y
[1] 126
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.36 0.038 0.0905
strata=LOW 18 4 3.64 0.035 0.0905
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2616 1.2989 0.8719 0.3 0.764
Likelihood ratio test=0.09 on 1 df, p=0.7612
n= 30, number of events= 7
============================
TCGA-COAD SIAH2
[1] 127
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.97 0.358 0.711
strata=LOW 12 3 4.03 0.264 0.711
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7155 0.4889 0.8668 -0.825 0.409
Likelihood ratio test=0.72 on 1 df, p=0.3949
n= 24, number of events= 7
============================
TCGA-COAD MIR29A
============================
TCGA-COAD CHAC1
[1] 128
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.43 1.72 2.91
strata=LOW 12 2 3.57 0.69 2.91
Chisq= 2.9 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.8994 0.1497 1.2324 -1.541 0.123
Likelihood ratio test=2.85 on 1 df, p=0.09116
n= 24, number of events= 5
============================
TCGA-COAD LINC00616
[1] 129
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.13 0.409 0.576
strata=LOW 31 10 8.87 0.144 0.576
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5868 1.7983 0.7841 0.748 0.454
Likelihood ratio test=0.63 on 1 df, p=0.4274
n= 43, number of events= 12
============================
TCGA-COAD PRKAA2
[1] 130
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.88 0.00711 0.0137
strata=LOW 12 5 5.12 0.00262 0.0137
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1181 0.8886 1.0096 -0.117 0.907
Likelihood ratio test=0.01 on 1 df, p=0.9069
n= 24, number of events= 7
============================
TCGA-COAD LONP1
[1] 131
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.24 0.256 0.488
strata=LOW 12 2 2.76 0.208 0.488
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6407 0.5269 0.9311 -0.688 0.491
Likelihood ratio test=0.48 on 1 df, p=0.4867
n= 24, number of events= 5
============================
TCGA-COAD PPARG
[1] 132
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.85 0.01223 0.032
strata=LOW 12 3 3.15 0.00718 0.032
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2187 0.8036 1.2258 -0.178 0.858
Likelihood ratio test=0.03 on 1 df, p=0.8568
n= 24, number of events= 5
============================
TCGA-COAD MAPK1
[1] 133
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.21 0.660 1.2
strata=LOW 12 4 2.79 0.522 1.2
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.167 3.213 1.124 1.039 0.299
Likelihood ratio test=1.31 on 1 df, p=0.2523
n= 24, number of events= 5
============================
TCGA-COAD PEX6
[1] 134
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.61 0.143 0.254
strata=LOW 12 5 4.39 0.085 0.254
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4339 1.5433 0.8677 0.5 0.617
Likelihood ratio test=0.26 on 1 df, p=0.6097
n= 24, number of events= 7
============================
TCGA-COAD PPARA
[1] 135
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 5.33 0.330 0.937
strata=LOW 12 5 3.67 0.479 0.937
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7083 2.0305 0.7453 0.95 0.342
Likelihood ratio test=0.93 on 1 df, p=0.3341
n= 24, number of events= 9
============================
TCGA-COAD ACSL4
[1] 136
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.93 0.944 2.53
strata=LOW 12 5 3.07 1.205 2.53
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.584 4.874 1.101 1.439 0.15
Likelihood ratio test=2.76 on 1 df, p=0.09639
n= 24, number of events= 7
============================
TCGA-COAD ANO6
[1] 137
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.12 0.00697 0.0132
strata=LOW 12 3 2.88 0.00513 0.0132
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1095 1.1157 0.9527 0.115 0.909
Likelihood ratio test=0.01 on 1 df, p=0.9083
n= 24, number of events= 5
============================
TCGA-COAD YTHDC2
[1] 138
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 4.18 1.14 3.28
strata=LOW 12 5 2.82 1.70 3.28
Chisq= 3.3 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.771 5.880 1.104 1.605 0.109
Likelihood ratio test=3.51 on 1 df, p=0.06096
n= 24, number of events= 7
============================
TCGA-COAD MIR103A1
============================
TCGA-COAD INTS2
[1] 139
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.42 0.829 2.79
strata=LOW 12 3 1.58 1.264 2.79
Chisq= 2.8 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.119e+01 1.593e+09 2.359e+04 0.001 0.999
Likelihood ratio test=3.93 on 1 df, p=0.04751
n= 24, number of events= 4
============================
TCGA-COAD PTPN6
[1] 140
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.14 0.237 0.766
strata=LOW 12 1 1.86 0.400 0.766
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9809 0.3750 1.1638 -0.843 0.399
Likelihood ratio test=0.81 on 1 df, p=0.3687
n= 24, number of events= 5
============================
TCGA-COAD SMAD7
[1] 141
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.37 0.0591 0.113
strata=LOW 12 3 2.63 0.0535 0.113
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3058 1.3578 0.9138 0.335 0.738
Likelihood ratio test=0.11 on 1 df, p=0.7358
n= 24, number of events= 5
============================
TCGA-COAD ATG16L1
[1] 142
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 4.53 1.41 3.7
strata=LOW 12 6 3.47 1.84 3.7
Chisq= 3.7 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.827 6.212 1.083 1.686 0.0918
Likelihood ratio test=4.09 on 1 df, p=0.04309
n= 24, number of events= 8
============================
TCGA-COAD LINC00976
[1] 143
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.08 0.00217 0.00448
strata=LOW 12 4 3.92 0.00171 0.00448
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05469 1.05621 0.81723 0.067 0.947
Likelihood ratio test=0 on 1 df, p=0.9466
n= 24, number of events= 7
============================
TCGA-COAD H19
[1] 144
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.32 0.0439 0.0821
strata=LOW 12 3 2.68 0.0380 0.0821
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2611 1.2983 0.9137 0.286 0.775
Likelihood ratio test=0.08 on 1 df, p=0.7735
n= 24, number of events= 5
============================
TCGA-COAD FADS1
[1] 145
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.41 1.044 1.81
strata=LOW 12 4 5.59 0.451 1.81
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1392 0.3201 0.8876 -1.283 0.199
Likelihood ratio test=1.78 on 1 df, p=0.1821
n= 24, number of events= 8
============================
TCGA-COAD CHP1
[1] 146
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.68 0.0388 0.0851
strata=LOW 12 3 3.32 0.0313 0.0851
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2682 0.7648 0.9218 -0.291 0.771
Likelihood ratio test=0.09 on 1 df, p=0.7694
n= 24, number of events= 6
============================
TCGA-COAD PRR5
[1] 147
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.2 1.48 4.53
strata=LOW 12 0 1.8 1.80 4.53
Chisq= 4.5 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.170e+01 3.768e-10 2.416e+04 -0.001 0.999
Likelihood ratio test=5.52 on 1 df, p=0.01875
n= 24, number of events= 4
============================
TCGA-COAD CFL1
[1] 148
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.53 0.0860 0.174
strata=LOW 12 2 2.47 0.0883 0.174
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3791 0.6845 0.9132 -0.415 0.678
Likelihood ratio test=0.18 on 1 df, p=0.6751
n= 24, number of events= 5
============================
TCGA-COAD MIR382
============================
TCGA-COAD LAMP2
[1] 149
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.93 0.00230 0.00678
strata=LOW 12 1 1.07 0.00417 0.00678
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1032 0.9020 1.2535 -0.082 0.934
Likelihood ratio test=0.01 on 1 df, p=0.9341
n= 24, number of events= 3
============================
TCGA-COAD PTPN14
[1] 150
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.98 0.000203 0.000411
strata=LOW 12 4 4.02 0.000150 0.000411
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.01674 0.98340 0.82575 -0.02 0.984
Likelihood ratio test=0 on 1 df, p=0.9838
n= 24, number of events= 7
============================
TCGA-COAD AGPAT3
[1] 151
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.42 0.590 1.64
strata=LOW 12 4 2.58 0.782 1.64
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.342 3.828 1.125 1.193 0.233
Likelihood ratio test=1.77 on 1 df, p=0.1836
n= 24, number of events= 6
============================
TCGA-COAD STING1
[1] 152
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.28 0.224 0.697
strata=LOW 12 1 1.72 0.298 0.697
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9828 0.3743 1.2251 -0.802 0.422
Likelihood ratio test=0.69 on 1 df, p=0.4056
n= 24, number of events= 4
============================
TCGA-COAD ABCC1
[1] 153
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.94 0.382 0.688
strata=LOW 12 3 4.06 0.277 0.688
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6410 0.5268 0.7842 -0.817 0.414
Likelihood ratio test=0.68 on 1 df, p=0.41
n= 24, number of events= 7
============================
TCGA-COAD IFNA5
============================
TCGA-COAD MIR140
============================
TCGA-COAD MYB
[1] 154
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 4.38 1.29 5.38
strata=LOW 12 4 1.62 3.48 5.38
Chisq= 5.4 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.224 9.244 1.139 1.952 0.0509
Likelihood ratio test=5.02 on 1 df, p=0.02501
n= 24, number of events= 6
============================
TCGA-COAD IFNA6
============================
TCGA-COAD IFNA14
============================
TCGA-COAD BDNF-AS
[1] 155
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.21 0.193 0.366
strata=LOW 12 5 5.79 0.107 0.366
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4653 0.6280 0.7751 -0.6 0.548
Likelihood ratio test=0.37 on 1 df, p=0.5455
n= 24, number of events= 9
============================
TCGA-COAD TRIB2
[1] 156
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 3.86 1.18 2.71
strata=LOW 12 2 4.14 1.10 2.71
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2920 0.2747 0.8389 -1.54 0.124
Likelihood ratio test=2.68 on 1 df, p=0.1014
n= 24, number of events= 8
============================
TCGA-COAD MALAT1
[1] 157
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.21 0.666 1.5
strata=LOW 12 5 3.79 0.389 1.5
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.323 3.755 1.158 1.142 0.253
Likelihood ratio test=1.53 on 1 df, p=0.2156
n= 24, number of events= 6
============================
TCGA-COAD FH
[1] 158
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.85 0.892 2.82
strata=LOW 12 4 2.15 1.602 2.82
Chisq= 2.8 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.681 5.371 1.120 1.5 0.134
Likelihood ratio test=2.9 on 1 df, p=0.08849
n= 24, number of events= 6
============================
TCGA-COAD PEX10
[1] 159
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.59 0.135 0.288
strata=LOW 12 4 3.41 0.103 0.288
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4927 1.6367 0.9260 0.532 0.595
Likelihood ratio test=0.29 on 1 df, p=0.5905
n= 24, number of events= 6
============================
TCGA-COAD SCD
[1] 160
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.32 0.0447 0.108
strata=LOW 12 2 1.68 0.0618 0.108
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3296 1.3905 1.0073 0.327 0.743
Likelihood ratio test=0.11 on 1 df, p=0.744
n= 24, number of events= 4
============================
TCGA-COAD FTL
[1] 161
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.01 6.89e-05 0.00018
strata=LOW 12 2 1.99 1.05e-04 0.00018
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.01247 1.01255 0.92985 0.013 0.989
Likelihood ratio test=0 on 1 df, p=0.9893
n= 24, number of events= 5
============================
TCGA-COAD TSC1
[1] 162
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.42 0.0515 0.121
strata=LOW 12 3 2.58 0.0683 0.121
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.284 1.328 0.820 0.346 0.729
Likelihood ratio test=0.12 on 1 df, p=0.7295
n= 24, number of events= 6
============================
TCGA-COAD BRD3
[1] 163
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.6 0.0342 0.084
strata=LOW 12 3 3.4 0.0463 0.084
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2153 0.8063 0.7444 -0.289 0.772
Likelihood ratio test=0.08 on 1 df, p=0.7708
n= 24, number of events= 8
============================
TCGA-COAD SLC16A1
[1] 164
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.21 0.0137 0.0362
strata=LOW 12 3 2.79 0.0158 0.0362
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1748 1.1911 0.9198 0.19 0.849
Likelihood ratio test=0.04 on 1 df, p=0.8485
n= 24, number of events= 6
============================
TCGA-COAD MIR132
============================
TCGA-COAD MIR375
============================
TCGA-COAD MIOX
[1] 165
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.85 0.465 1.36
strata=LOW 12 1 2.15 0.616 1.36
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2683 0.2813 1.1609 -1.092 0.275
Likelihood ratio test=1.39 on 1 df, p=0.2377
n= 24, number of events= 5
============================
TCGA-COAD ATXN8OS
============================
TCGA-COAD KLHDC3
[1] 166
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.51 0.0734 0.154
strata=LOW 12 5 4.49 0.0573 0.154
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3058 1.3578 0.7827 0.391 0.696
Likelihood ratio test=0.15 on 1 df, p=0.6943
n= 24, number of events= 8
============================
TCGA-COAD MICU1
[1] 167
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.55 0.0581 0.172
strata=LOW 12 2 2.45 0.0839 0.172
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3849 0.6805 0.9323 -0.413 0.68
Likelihood ratio test=0.17 on 1 df, p=0.677
n= 24, number of events= 6
============================
TCGA-COAD CBS
[1] 168
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.35 0.126 0.295
strata=LOW 12 3 3.65 0.115 0.295
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4409 0.6435 0.8177 -0.539 0.59
Likelihood ratio test=0.29 on 1 df, p=0.5913
n= 24, number of events= 7
============================
TCGA-COAD HUWE1
[1] 169
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.06 0.00200 0.00426
strata=LOW 12 2 1.94 0.00213 0.00426
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.06626 1.06851 1.01577 0.065 0.948
Likelihood ratio test=0 on 1 df, p=0.948
n= 24, number of events= 4
============================
TCGA-COAD LINC00472
[1] 170
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.57 0.0736 0.152
strata=LOW 12 4 4.43 0.0426 0.152
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3539 0.7019 0.9138 -0.387 0.699
Likelihood ratio test=0.15 on 1 df, p=0.6959
n= 24, number of events= 7
============================
TCGA-COAD FGF21
============================
TCGA-COAD MIR34A
============================
TCGA-COAD IDH1
[1] 171
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.1 0.390 1.01
strata=LOW 12 4 2.9 0.416 1.01
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.076 2.934 1.124 0.958 0.338
Likelihood ratio test=1.1 on 1 df, p=0.2938
n= 24, number of events= 6
============================
TCGA-COAD GSK3B
[1] 172
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 2.59 2.59 7.45
strata=LOW 12 4 1.41 4.79 7.45
Chisq= 7.5 on 1 degrees of freedom, p= 0.006
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.204e+01 3.738e+09 2.218e+04 0.001 0.999
Likelihood ratio test=8.44 on 1 df, p=0.003673
n= 24, number of events= 4
============================
TCGA-COAD KDM4A
[1] 173
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.47 0.0628 0.293
strata=LOW 12 2 1.53 0.1421 0.293
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.655 1.925 1.230 0.532 0.594
Likelihood ratio test=0.3 on 1 df, p=0.584
n= 24, number of events= 5
============================
TCGA-COAD PEX12
[1] 174
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.97 0.000401 0.000686
strata=LOW 12 4 4.03 0.000196 0.000686
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.02434 0.97595 0.92919 -0.026 0.979
Likelihood ratio test=0 on 1 df, p=0.9791
n= 24, number of events= 6
============================
TCGA-COAD IDO1
[1] 175
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 5.04 0.216 0.659
strata=LOW 12 4 2.96 0.368 0.659
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6237 1.8659 0.7795 0.8 0.424
Likelihood ratio test=0.65 on 1 df, p=0.42
n= 24, number of events= 8
============================
TCGA-COAD BCAT2
[1] 176
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.89 0.00390 0.00779
strata=LOW 12 3 3.11 0.00363 0.00779
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07328 0.92934 0.83038 -0.088 0.93
Likelihood ratio test=0.01 on 1 df, p=0.9297
n= 24, number of events= 6
============================
TCGA-COAD ADAM23
[1] 177
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.61 0.059 0.105
strata=LOW 12 4 4.39 0.035 0.105
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2636 0.7683 0.8173 -0.322 0.747
Likelihood ratio test=0.1 on 1 df, p=0.7474
n= 24, number of events= 7
============================
TCGA-COAD PEX3
[1] 178
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.33 0.758 1.82
strata=LOW 12 3 1.67 1.055 1.82
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.433 4.190 1.156 1.24 0.215
Likelihood ratio test=1.82 on 1 df, p=0.1771
n= 24, number of events= 4
============================
TCGA-COAD ATP5MC3
[1] 179
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.5 0.0994 0.172
strata=LOW 12 5 4.5 0.0551 0.172
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3595 1.4326 0.8705 0.413 0.68
Likelihood ratio test=0.18 on 1 df, p=0.6744
n= 24, number of events= 7
============================
TCGA-COAD AQP5
[1] 180
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.76 0.208 0.474
strata=LOW 12 3 2.24 0.256 0.474
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6274 1.8727 0.9248 0.678 0.498
Likelihood ratio test=0.47 on 1 df, p=0.4919
n= 24, number of events= 5
============================
TCGA-COAD ADAMTS9-AS1
[1] 181
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 3.3 1.60 3.58
strata=LOW 12 5 2.7 1.96 3.58
Chisq= 3.6 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.817 6.155 1.097 1.657 0.0975
Likelihood ratio test=3.79 on 1 df, p=0.05144
n= 24, number of events= 6
============================
TCGA-COAD ACSL3
[1] 182
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.66 0.164 0.48
strata=LOW 12 3 2.34 0.186 0.48
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8017 2.2293 1.1839 0.677 0.498
Likelihood ratio test=0.51 on 1 df, p=0.4761
n= 24, number of events= 5
============================
TCGA-COAD DDR2
[1] 183
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.25 0.0199 0.0437
strata=LOW 12 3 2.75 0.0236 0.0437
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1707 1.1861 0.8178 0.209 0.835
Likelihood ratio test=0.04 on 1 df, p=0.8348
n= 24, number of events= 6
============================
TCGA-COAD TERT
[1] 184
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2 0.494 0.745
strata=LOW 12 3 4 0.248 0.745
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6929 0.5001 0.8186 -0.846 0.397
Likelihood ratio test=0.7 on 1 df, p=0.4018
n= 24, number of events= 6
============================
TCGA-COAD IFNA7
============================
TCGA-COAD ECH1
[1] 185
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.81 0.506 0.961
strata=LOW 12 3 4.19 0.339 0.961
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8291 0.4364 0.8697 -0.953 0.34
Likelihood ratio test=0.97 on 1 df, p=0.3247
n= 24, number of events= 7
============================
TCGA-COAD CS
[1] 186
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.55 0.0845 0.174
strata=LOW 12 4 3.45 0.0868 0.174
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3193 1.3761 0.7691 0.415 0.678
Likelihood ratio test=0.17 on 1 df, p=0.6764
n= 24, number of events= 7
============================
TCGA-COAD AMN
[1] 187
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.39 1.083 1.81
strata=LOW 12 2 3.61 0.717 1.81
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1088 0.3299 0.8675 -1.278 0.201
Likelihood ratio test=1.76 on 1 df, p=0.1844
n= 24, number of events= 6
============================
TCGA-COAD DUOX2
[1] 188
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.45 0.0884 0.181
strata=LOW 12 3 3.55 0.0858 0.181
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3297 0.7192 0.7778 -0.424 0.672
Likelihood ratio test=0.18 on 1 df, p=0.6701
n= 24, number of events= 7
============================
TCGA-COAD MBOAT1
[1] 189
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.85 0.00577 0.0112
strata=LOW 12 5 5.15 0.00431 0.0112
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07512 0.92763 0.70979 -0.106 0.916
Likelihood ratio test=0.01 on 1 df, p=0.9157
n= 24, number of events= 9
============================
TCGA-COAD RNF113A
[1] 190
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.49 0.103 0.278
strata=LOW 12 1 1.51 0.171 0.278
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6022 0.5476 1.1601 -0.519 0.604
Likelihood ratio test=0.29 on 1 df, p=0.5875
n= 24, number of events= 4
============================
TCGA-COAD MIR138-1
============================
TCGA-COAD MIR144
============================
TCGA-COAD P4HB
[1] 191
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.63 1.160 1.98
strata=LOW 12 2 3.37 0.559 1.98
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4938 0.2245 1.1597 -1.288 0.198
Likelihood ratio test=1.97 on 1 df, p=0.1606
n= 24, number of events= 5
============================
TCGA-COAD MIR338
============================
TCGA-COAD PTGS2
[1] 192
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.97 0.353 0.626
strata=LOW 12 4 5.03 0.209 0.626
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6013 0.5481 0.7710 -0.78 0.435
Likelihood ratio test=0.62 on 1 df, p=0.4323
n= 24, number of events= 8
============================
TCGA-COAD ASAH2
[1] 193
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.32 0.346 0.621
strata=LOW 12 2 2.68 0.171 0.621
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9327 0.3935 1.2262 -0.761 0.447
Likelihood ratio test=0.62 on 1 df, p=0.4308
n= 24, number of events= 4
============================
TCGA-COAD MIR522
============================
TCGA-COAD GALNT14
[1] 194
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.45 0.691 2.06
strata=LOW 12 1 2.55 0.938 2.06
Chisq= 2.1 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4984 0.2235 1.1354 -1.32 0.187
Likelihood ratio test=2.16 on 1 df, p=0.1413
n= 24, number of events= 6
============================
TCGA-COAD KDM4C
[1] 195
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.18 0.01558 0.0344
strata=LOW 12 4 3.82 0.00892 0.0344
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1856 1.2040 1.0017 0.185 0.853
Likelihood ratio test=0.03 on 1 df, p=0.8531
n= 24, number of events= 6
============================
TCGA-COAD FXN
[1] 196
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.27 0.0328 0.102
strata=LOW 12 2 1.73 0.0431 0.102
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3883 1.4745 1.2252 0.317 0.751
Likelihood ratio test=0.1 on 1 df, p=0.7467
n= 24, number of events= 4
============================
TCGA-COAD MEF2C
[1] 197
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.55 0.0842 0.206
strata=LOW 12 4 3.45 0.0864 0.206
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3693 1.4467 0.8176 0.452 0.652
Likelihood ratio test=0.2 on 1 df, p=0.6524
n= 24, number of events= 7
============================
TCGA-COAD MDM2
[1] 198
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.6 0.0622 0.114
strata=LOW 12 3 3.4 0.0475 0.114
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2794 0.7562 0.8317 -0.336 0.737
Likelihood ratio test=0.11 on 1 df, p=0.7372
n= 24, number of events= 6
============================
TCGA-COAD MAP3K14
[1] 199
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.38 0.776 1.82
strata=LOW 12 1 2.62 1.001 1.82
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3791 0.2518 1.1023 -1.251 0.211
Likelihood ratio test=2.03 on 1 df, p=0.1544
n= 24, number of events= 6
============================
TCGA-COAD MDM4
[1] 200
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.7 0.779 1.75
strata=LOW 12 5 3.3 0.872 1.75
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0767 2.9351 0.8503 1.266 0.205
Likelihood ratio test=1.77 on 1 df, p=0.1828
n= 24, number of events= 7
============================
TCGA-COAD ASMTL-AS1
[1] 201
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.08 0.00234 0.00483
strata=LOW 12 3 2.92 0.00248 0.00483
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05676 1.05841 0.81725 0.069 0.945
Likelihood ratio test=0 on 1 df, p=0.9446
n= 24, number of events= 6
============================
TCGA-COAD NEAT1
[1] 202
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.72 0.0463 0.0884
strata=LOW 12 2 2.28 0.0349 0.0884
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3098 0.7336 1.0450 -0.296 0.767
Likelihood ratio test=0.09 on 1 df, p=0.7672
n= 24, number of events= 4
============================
TCGA-COAD COPZ1
[1] 203
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.35 0.178 0.337
strata=LOW 12 3 3.65 0.115 0.337
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5250 0.5915 0.9141 -0.574 0.566
Likelihood ratio test=0.34 on 1 df, p=0.5611
n= 24, number of events= 6
============================
TCGA-COAD PLIN2
[1] 204
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.52 0.0669 0.163
strata=LOW 12 3 3.48 0.0675 0.163
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3488 0.7055 0.8690 -0.401 0.688
Likelihood ratio test=0.17 on 1 df, p=0.6831
n= 24, number of events= 7
============================
TCGA-COAD FADS2
[1] 205
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.59 0.1029 0.185
strata=LOW 12 4 4.41 0.0373 0.185
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4486 0.6385 1.0495 -0.427 0.669
Likelihood ratio test=0.18 on 1 df, p=0.6693
n= 24, number of events= 6
============================
TCGA-COAD MIR7-1
============================
TCGA-COAD TXN
[1] 206
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.93 0.00131 0.00346
strata=LOW 12 3 3.07 0.00168 0.00346
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04814 0.95300 0.81842 -0.059 0.953
Likelihood ratio test=0 on 1 df, p=0.9531
n= 24, number of events= 7
============================
TCGA-COAD MIR302A
============================
TCGA-COAD EGLN2
[1] 207
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.84 0.185 0.414
strata=LOW 12 4 3.16 0.225 0.414
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4885 1.6299 0.7670 0.637 0.524
Likelihood ratio test=0.41 on 1 df, p=0.5214
n= 24, number of events= 7
============================
TCGA-COAD NCOA3
[1] 208
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.7 0.133 0.351
strata=LOW 12 3 2.3 0.215 0.351
Chisq= 0.4 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4818 1.6190 0.8206 0.587 0.557
Likelihood ratio test=0.34 on 1 df, p=0.559
n= 24, number of events= 6
============================
TCGA-COAD SREBF1
[1] 209
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.52 1.433 2.34
strata=LOW 12 1 2.48 0.881 2.34
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.6009 0.2017 1.1592 -1.381 0.167
Likelihood ratio test=2.28 on 1 df, p=0.1313
n= 24, number of events= 4
============================
TCGA-COAD LINC01134
[1] 210
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.46 0.1171 0.241
strata=LOW 12 3 3.54 0.0815 0.241
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4555 0.6341 0.9339 -0.488 0.626
Likelihood ratio test=0.24 on 1 df, p=0.6221
n= 24, number of events= 6
============================
TCGA-COAD MYCN
[1] 211
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.56 0.124 0.334
strata=LOW 12 3 2.44 0.131 0.334
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6556 1.9264 1.1549 0.568 0.57
Likelihood ratio test=0.36 on 1 df, p=0.5513
n= 24, number of events= 5
============================
TCGA-COAD IFNA4
============================
TCGA-COAD DPEP1
[1] 212
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.53 0.112 0.228
strata=LOW 12 3 2.47 0.115 0.228
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4324 1.5410 0.9132 0.474 0.636
Likelihood ratio test=0.23 on 1 df, p=0.6322
n= 24, number of events= 5
============================
TCGA-COAD VDAC2
[1] 213
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.7 0.287 0.505
strata=LOW 12 4 3.3 0.148 0.505
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8028 2.2318 1.1595 0.692 0.489
Likelihood ratio test=0.54 on 1 df, p=0.4639
n= 24, number of events= 5
============================
TCGA-COAD PCBP2-OT1
[1] 214
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3 0.335 0.689
strata=LOW 12 4 3 0.336 0.689
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7123 2.0387 0.8751 0.814 0.416
Likelihood ratio test=0.7 on 1 df, p=0.4023
n= 24, number of events= 6
============================
TCGA-COAD KEAP1
[1] 215
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.8 0.0139 0.0261
strata=LOW 12 3 3.2 0.0122 0.0261
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1321 0.8762 0.8178 -0.162 0.872
Likelihood ratio test=0.03 on 1 df, p=0.8717
n= 24, number of events= 6
============================
TCGA-COAD RPL8
[1] 216
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.93 0.392 0.775
strata=LOW 12 3 4.07 0.282 0.775
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7488 0.4730 0.8702 -0.86 0.39
Likelihood ratio test=0.79 on 1 df, p=0.3751
n= 24, number of events= 7
============================
TCGA-COAD ALOX12
[1] 217
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 3.03 2.91 6.02
strata=LOW 12 0 2.97 2.97 6.02
Chisq= 6 on 1 degrees of freedom, p= 0.01
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.124e+01 5.971e-10 1.655e+04 -0.001 0.999
Likelihood ratio test=8.32 on 1 df, p=0.003917
n= 24, number of events= 6
============================
TCGA-COAD ACSF2
[1] 218
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.22 0.0215 0.05
strata=LOW 12 2 1.78 0.0267 0.05
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2276 1.2556 1.0198 0.223 0.823
Likelihood ratio test=0.05 on 1 df, p=0.8235
n= 24, number of events= 4
============================
TCGA-COAD KDM5A
[1] 219
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.95 1.29 5.56
strata=LOW 12 3 1.05 3.59 5.56
Chisq= 5.6 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.202e+01 3.667e+09 2.558e+04 0.001 0.999
Likelihood ratio test=6.3 on 1 df, p=0.01209
n= 24, number of events= 4
============================
TCGA-COAD NRAS
[1] 220
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.59 0.976 2.1
strata=LOW 12 4 2.41 1.048 2.1
Chisq= 2.1 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.497 4.467 1.127 1.328 0.184
Likelihood ratio test=2.21 on 1 df, p=0.1368
n= 24, number of events= 5
============================
TCGA-COAD MIR30E
============================
TCGA-COAD OGFRP1
[1] 221
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.83 0.182 0.435
strata=LOW 12 5 4.17 0.167 0.435
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5557 1.7431 0.8526 0.652 0.515
Likelihood ratio test=0.45 on 1 df, p=0.5014
n= 24, number of events= 8
============================
TCGA-COAD TF
[1] 222
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.47 0.676 1.4
strata=LOW 12 3 4.53 0.518 1.4
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9798 0.3754 0.8579 -1.142 0.253
Likelihood ratio test=1.45 on 1 df, p=0.2288
n= 24, number of events= 8
============================
TCGA-COAD ETV4
[1] 223
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.5 0.169 0.339
strata=LOW 12 2 1.5 0.170 0.339
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7001 2.0141 1.2262 0.571 0.568
Likelihood ratio test=0.35 on 1 df, p=0.5564
n= 24, number of events= 3
============================
TCGA-COAD PLA2G6
[1] 224
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.7 1.003 1.52
strata=LOW 12 2 3.3 0.515 1.52
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0748 0.3414 0.9138 -1.176 0.24
Likelihood ratio test=1.42 on 1 df, p=0.2338
n= 24, number of events= 5
============================
TCGA-COAD POR
[1] 225
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.85 0.0123 0.0465
strata=LOW 12 1 1.15 0.0197 0.0465
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3040 0.7379 1.4147 -0.215 0.83
Likelihood ratio test=0.05 on 1 df, p=0.8302
n= 24, number of events= 3
============================
TCGA-COAD BRPF1
[1] 226
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.92 0.171 0.698
strata=LOW 12 3 2.08 0.405 0.698
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7476 2.1120 0.9156 0.817 0.414
Likelihood ratio test=0.68 on 1 df, p=0.4079
n= 24, number of events= 7
============================
TCGA-COAD TMBIM4
[1] 227
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.53 0.923 1.66
strata=LOW 12 5 3.47 0.672 1.66
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.328 3.775 1.105 1.202 0.229
Likelihood ratio test=1.85 on 1 df, p=0.1739
n= 24, number of events= 6
============================
TCGA-COAD KRAS
[1] 228
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.99 0.993 3.3
strata=LOW 12 4 2.01 1.970 3.3
Chisq= 3.3 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.784 5.955 1.118 1.596 0.111
Likelihood ratio test=3.32 on 1 df, p=0.06859
n= 24, number of events= 6
============================
TCGA-COAD AHCY
[1] 229
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.2 0.0182 0.0337
strata=LOW 12 4 3.8 0.0105 0.0337
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1703 1.1857 0.9290 0.183 0.855
Likelihood ratio test=0.03 on 1 df, p=0.8539
n= 24, number of events= 6
============================
TCGA-COAD MIR34C
============================
TCGA-COAD ATG3
[1] 230
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.33 0.0319 0.0745
strata=LOW 12 4 3.67 0.0288 0.0745
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2267 1.2545 0.8324 0.272 0.785
Likelihood ratio test=0.07 on 1 df, p=0.7856
n= 24, number of events= 7
============================
TCGA-COAD MIR30B
============================
TCGA-COAD LYRM1
[1] 231
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 4.03 1.03 2.79
strata=LOW 12 5 2.97 1.40 2.79
Chisq= 2.8 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.647 5.190 1.098 1.499 0.134
Likelihood ratio test=3.03 on 1 df, p=0.08159
n= 24, number of events= 7
============================
TCGA-COAD SIRT6
[1] 232
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.72 0.0443 0.111
strata=LOW 12 2 2.28 0.0335 0.111
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4171 0.6590 1.2588 -0.331 0.74
Likelihood ratio test=0.11 on 1 df, p=0.7361
n= 24, number of events= 4
============================
TCGA-COAD KMT2D
[1] 233
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.99 0.344 0.631
strata=LOW 12 3 4.01 0.256 0.631
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6183 0.5389 0.7892 -0.783 0.433
Likelihood ratio test=0.63 on 1 df, p=0.429
n= 24, number of events= 7
============================
TCGA-COAD LPIN1
[1] 234
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.01 0.340 1.03
strata=LOW 12 3 1.99 0.515 1.03
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.113 3.043 1.156 0.963 0.336
Likelihood ratio test=1.07 on 1 df, p=0.3002
n= 24, number of events= 5
============================
TCGA-COAD MBOAT2
[1] 235
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.59 0.0660 0.183
strata=LOW 12 2 2.41 0.0708 0.183
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4300 0.6505 1.0133 -0.424 0.671
Likelihood ratio test=0.18 on 1 df, p=0.6723
n= 24, number of events= 5
============================
TCGA-COAD KDM3B
[1] 236
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.6 0.556 1.8
strata=LOW 12 4 2.4 1.066 1.8
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.1110 3.0374 0.8704 1.276 0.202
Likelihood ratio test=1.76 on 1 df, p=0.1852
n= 24, number of events= 7
============================
TCGA-COAD ARHGEF26-AS1
[1] 237
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.69 0.281 0.486
strata=LOW 13 4 3.31 0.143 0.486
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7858 2.1942 1.1557 0.68 0.497
Likelihood ratio test=0.52 on 1 df, p=0.472
n= 25, number of events= 5
============================
TCGA-COAD MIR9-1
============================
TCGA-COAD AIFM2
[1] 238
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.43 0.135 0.355
strata=LOW 12 2 2.57 0.128 0.355
Chisq= 0.4 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6828 0.5052 1.1674 -0.585 0.559
Likelihood ratio test=0.38 on 1 df, p=0.5396
n= 24, number of events= 5
============================
TCGA-COAD PRDX1
[1] 239
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.77 0.0140 0.0308
strata=LOW 12 3 3.23 0.0163 0.0308
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1352 0.8736 0.7705 -0.175 0.861
Likelihood ratio test=0.03 on 1 df, p=0.8603
n= 24, number of events= 7
============================
TCGA-COAD FOXO4
[1] 240
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.45 0.058 0.217
strata=LOW 12 2 1.55 0.129 0.217
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4706 1.6010 1.0180 0.462 0.644
Likelihood ratio test=0.21 on 1 df, p=0.6451
n= 24, number of events= 5
============================
TCGA-COAD BMAL1
[1] 241
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.95 0.308 0.755
strata=LOW 12 4 3.05 0.299 0.755
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7748 2.1701 0.9137 0.848 0.396
Likelihood ratio test=0.74 on 1 df, p=0.3901
n= 24, number of events= 6
============================
TCGA-COAD MIR127
============================
TCGA-COAD TGFBR1
[1] 242
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.23 0.263 0.596
strata=LOW 12 1 1.77 0.332 0.596
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8647 0.4212 1.1554 -0.748 0.454
Likelihood ratio test=0.63 on 1 df, p=0.4265
n= 24, number of events= 4
============================
TCGA-COAD NR1D2
[1] 243
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.31 0.0414 0.0982
strata=LOW 12 2 1.69 0.0565 0.0982
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3126 1.3670 1.0015 0.312 0.755
Likelihood ratio test=0.1 on 1 df, p=0.7554
n= 24, number of events= 4
============================
TCGA-COAD FZD7
[1] 244
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.35 2.01 3.66
strata=LOW 12 1 2.65 1.03 3.66
Chisq= 3.7 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.142e+01 4.986e-10 2.341e+04 -0.001 0.999
Likelihood ratio test=4.78 on 1 df, p=0.02875
n= 24, number of events= 4
============================
TCGA-COAD G6PD
[1] 245
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.45 0.124 0.404
strata=LOW 12 1 1.55 0.195 0.404
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7604 0.4675 1.2250 -0.621 0.535
Likelihood ratio test=0.41 on 1 df, p=0.5219
n= 24, number of events= 4
============================
TCGA-COAD HRAS
[1] 246
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.75 0.565 1.58
strata=LOW 12 1 2.25 0.692 1.58
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3507 0.2591 1.1559 -1.169 0.243
Likelihood ratio test=1.61 on 1 df, p=0.2045
n= 24, number of events= 5
============================
TCGA-COAD SLC38A1
[1] 247
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.07 0.00249 0.00517
strata=LOW 12 3 2.93 0.00176 0.00517
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07191 1.07456 1.00074 0.072 0.943
Likelihood ratio test=0.01 on 1 df, p=0.9427
n= 24, number of events= 5
============================
TCGA-COAD SLC39A14
[1] 248
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.07 0.283 1.2
strata=LOW 12 3 1.93 0.599 1.2
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.213 3.363 1.170 1.036 0.3
Likelihood ratio test=1.24 on 1 df, p=0.2648
n= 24, number of events= 6
============================
TCGA-COAD MIR21
============================
TCGA-COAD MIR1-1
============================
TCGA-COAD PROM2
[1] 249
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.38 0.0601 0.118
strata=LOW 12 4 3.62 0.0395 0.118
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3164 1.3721 0.9250 0.342 0.732
Likelihood ratio test=0.12 on 1 df, p=0.7302
n= 24, number of events= 6
============================
TCGA-COAD NFE2L2
[1] 250
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.14 0.416 1.35
strata=LOW 12 3 1.86 0.705 1.35
Chisq= 1.3 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.270 3.562 1.164 1.091 0.275
Likelihood ratio test=1.39 on 1 df, p=0.2387
n= 24, number of events= 5
============================
TCGA-COAD GABARAPL1
[1] 251
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 2.68 2.00 3.75
strata=LOW 12 2 4.32 1.24 3.75
Chisq= 3.8 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.8937 0.1505 1.1130 -1.701 0.0889
Likelihood ratio test=3.98 on 1 df, p=0.04597
n= 24, number of events= 7
============================
TCGA-COAD MIR335
============================
TCGA-COAD PTEN
[1] 252
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2 3.14e-06 6.29e-06
strata=LOW 12 3 3 2.09e-06 6.29e-06
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.002509 0.997494 1.000630 -0.003 0.998
Likelihood ratio test=0 on 1 df, p=0.998
n= 24, number of events= 5
============================
TCGA-COAD PARP4
[1] 253
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.93 0.00289 0.0057
strata=LOW 12 3 3.07 0.00181 0.0057
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07629 0.92655 1.01091 -0.075 0.94
Likelihood ratio test=0.01 on 1 df, p=0.9398
n= 24, number of events= 5
============================
TCGA-COAD MS4A15
[1] 254
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.42 0.590 1.39
strata=LOW 12 5 3.58 0.564 1.39
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9908 2.6934 0.8724 1.136 0.256
Likelihood ratio test=1.38 on 1 df, p=0.2393
n= 24, number of events= 7
============================
TCGA-COAD TIMM9
[1] 255
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.18 0.0148 0.027
strata=LOW 12 3 2.82 0.0114 0.027
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1521 1.1643 0.9261 0.164 0.87
Likelihood ratio test=0.03 on 1 df, p=0.869
n= 24, number of events= 5
============================
TCGA-COAD PARP3
[1] 256
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.06 0.00100 0.00317
strata=LOW 12 2 1.94 0.00158 0.00317
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05722 1.05889 1.01643 0.056 0.955
Likelihood ratio test=0 on 1 df, p=0.9551
n= 24, number of events= 5
============================
TCGA-COAD WIPI1
[1] 257
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.8 0.382 0.837
strata=LOW 12 3 4.2 0.345 0.837
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7485 0.4731 0.8373 -0.894 0.371
Likelihood ratio test=0.87 on 1 df, p=0.3503
n= 24, number of events= 8
============================
TCGA-COAD SNX5
[1] 258
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.85 0.00839 0.0162
strata=LOW 12 3 3.15 0.00757 0.0162
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1049 0.9004 0.8238 -0.127 0.899
Likelihood ratio test=0.02 on 1 df, p=0.8986
n= 24, number of events= 6
============================
TCGA-COAD LINC00239
[1] 259
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.38 0.0425 0.0979
strata=LOW 12 3 2.62 0.0549 0.0979
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2555 1.2911 0.8187 0.312 0.755
Likelihood ratio test=0.1 on 1 df, p=0.7553
n= 24, number of events= 6
============================
TCGA-COAD PIEZO1
[1] 260
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 0.865 0.02090 0.0369
strata=LOW 12 2 2.135 0.00848 0.0369
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2708 0.7628 1.4146 -0.191 0.848
Likelihood ratio test=0.04 on 1 df, p=0.8484
n= 24, number of events= 3
============================
TCGA-COAD AKR1C2
[1] 261
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.11 0.00371 0.00817
strata=LOW 12 4 3.89 0.00296 0.00817
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07603 1.07899 0.84119 0.09 0.928
Likelihood ratio test=0.01 on 1 df, p=0.928
n= 24, number of events= 7
============================
TCGA-COAD MIR4443
============================
TCGA-COAD SLC16A1-AS1
[1] 262
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.64 1.02 2.19
strata=LOW 12 4 2.36 1.13 2.19
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.527 4.604 1.128 1.354 0.176
Likelihood ratio test=2.32 on 1 df, p=0.1277
n= 24, number of events= 5
============================
TCGA-COAD FAR1
[1] 263
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.258 1.26 3.4
strata=LOW 12 2 0.742 2.13 3.4
Chisq= 3.4 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.187e+01 3.159e+09 3.046e+04 0.001 0.999
Likelihood ratio test=3.97 on 1 df, p=0.04627
n= 24, number of events= 2
============================
TCGA-COAD CISD2
[1] 264
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.29 0.220 0.406
strata=LOW 12 2 2.71 0.186 0.406
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5737 0.5634 0.9133 -0.628 0.53
Likelihood ratio test=0.4 on 1 df, p=0.5247
n= 24, number of events= 5
============================
TCGA-COAD MAPK3
[1] 265
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.54 0.838 1.46
strata=LOW 12 3 4.46 0.477 1.46
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0081 0.3649 0.8686 -1.161 0.246
Likelihood ratio test=1.45 on 1 df, p=0.2288
n= 24, number of events= 7
============================
TCGA-COAD CYGB
[1] 266
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.34 0.130 0.26
strata=LOW 12 4 4.66 0.093 0.26
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3957 0.6732 0.7804 -0.507 0.612
Likelihood ratio test=0.26 on 1 df, p=0.6103
n= 24, number of events= 8
============================
TCGA-COAD MLST8
[1] 267
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.03 0.000252 0.000519
strata=LOW 12 3 2.97 0.000256 0.000519
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.01882 1.01900 0.82562 0.023 0.982
Likelihood ratio test=0 on 1 df, p=0.9818
n= 24, number of events= 6
============================
TCGA-COAD PANX2
[1] 268
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.83 0.356 0.918
strata=LOW 12 2 3.17 0.431 0.918
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8102 0.4448 0.8683 -0.933 0.351
Likelihood ratio test=0.93 on 1 df, p=0.3352
n= 24, number of events= 7
============================
TCGA-COAD PEBP1
[1] 269
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.33 0.103 0.359
strata=LOW 12 2 2.67 0.167 0.359
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5411 0.5821 0.9135 -0.592 0.554
Likelihood ratio test=0.36 on 1 df, p=0.5488
n= 24, number of events= 7
============================
TCGA-COAD PARP8
[1] 270
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.46 0.862 1.74
strata=LOW 12 4 2.54 0.832 1.74
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.378 3.966 1.125 1.224 0.221
Likelihood ratio test=1.86 on 1 df, p=0.1723
n= 24, number of events= 5
============================
TCGA-COAD GJA1
[1] 271
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.25 0.942 1.77
strata=LOW 12 3 4.75 0.644 1.77
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0661 0.3444 0.8391 -1.27 0.204
Likelihood ratio test=1.8 on 1 df, p=0.1792
n= 24, number of events= 8
============================
TCGA-COAD BAP1
[1] 272
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.39 0.439 0.998
strata=LOW 12 5 3.61 0.532 0.998
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7270 2.0688 0.7423 0.979 0.327
Likelihood ratio test=1 on 1 df, p=0.3177
n= 24, number of events= 8
============================
TCGA-COAD MAP3K11
[1] 273
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.47 0.112 0.37
strata=LOW 12 1 1.53 0.181 0.37
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7287 0.4825 1.2251 -0.595 0.552
Likelihood ratio test=0.38 on 1 df, p=0.5397
n= 24, number of events= 4
============================
TCGA-COAD TTBK2
[1] 274
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.2 0.202 0.436
strata=LOW 12 3 3.8 0.170 0.436
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5670 0.5672 0.8700 -0.652 0.515
Likelihood ratio test=0.45 on 1 df, p=0.5038
n= 24, number of events= 7
============================
TCGA-COAD MIR214
============================
TCGA-COAD PARP15
[1] 275
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 5.07 0.228 0.705
strata=LOW 12 4 2.93 0.395 0.705
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6458 1.9075 0.7811 0.827 0.408
Likelihood ratio test=0.69 on 1 df, p=0.4048
n= 24, number of events= 8
============================
TCGA-COAD HDDC3
[1] 276
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.8 0.01063 0.0204
strata=LOW 12 4 4.2 0.00961 0.0204
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1011 0.9038 0.7091 -0.143 0.887
Likelihood ratio test=0.02 on 1 df, p=0.8866
n= 24, number of events= 8
============================
TCGA-COAD MIR10A
============================
TCGA-COAD CGAS
[1] 277
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.2 0.203 0.344
strata=LOW 12 4 4.8 0.135 0.344
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4164 0.6594 0.7147 -0.583 0.56
Likelihood ratio test=0.34 on 1 df, p=0.5614
n= 24, number of events= 8
============================
TCGA-COAD SIRT2
[1] 278
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.52 0.0898 0.254
strata=LOW 12 2 2.48 0.0916 0.254
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5831 0.5581 1.1732 -0.497 0.619
Likelihood ratio test=0.27 on 1 df, p=0.6046
n= 24, number of events= 5
============================
TCGA-COAD PPARD
[1] 279
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.91 0.623 1.02
strata=LOW 12 3 4.09 0.291 1.02
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9001 0.4065 0.9196 -0.979 0.328
Likelihood ratio test=0.98 on 1 df, p=0.3211
n= 24, number of events= 6
============================
TCGA-COAD EGR1
[1] 280
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.17 0.220 0.414
strata=LOW 12 4 4.83 0.144 0.414
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4954 0.6094 0.7770 -0.638 0.524
Likelihood ratio test=0.41 on 1 df, p=0.5207
n= 24, number of events= 8
============================
TCGA-COAD AQP3
[1] 281
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.79 0.166 0.441
strata=LOW 12 4 3.21 0.196 0.441
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5807 1.7873 0.8853 0.656 0.512
Likelihood ratio test=0.45 on 1 df, p=0.5013
n= 24, number of events= 7
============================
TCGA-COAD HSF1
[1] 282
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.44 0.126 0.413
strata=LOW 12 1 1.56 0.199 0.413
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7680 0.4639 1.2251 -0.627 0.531
Likelihood ratio test=0.42 on 1 df, p=0.5177
n= 24, number of events= 4
============================
TCGA-COAD MIR18A
============================
TCGA-COAD OSBPL9
[1] 283
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.97 0.000377 0.000759
strata=LOW 12 2 2.03 0.000366 0.000759
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.02785 0.97253 1.01083 -0.028 0.978
Likelihood ratio test=0 on 1 df, p=0.978
n= 24, number of events= 4
============================
TCGA-COAD SESN2
[1] 284
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.24 1.376 2.63
strata=LOW 12 2 3.76 0.821 2.63
Chisq= 2.6 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.655 0.191 1.131 -1.464 0.143
Likelihood ratio test=2.72 on 1 df, p=0.09928
n= 24, number of events= 6
============================
TCGA-COAD BECN1
[1] 285
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.79 0.0116 0.0257
strata=LOW 12 4 4.21 0.0104 0.0257
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1233 0.8840 0.7702 -0.16 0.873
Likelihood ratio test=0.03 on 1 df, p=0.8725
n= 24, number of events= 8
============================
TCGA-COAD FTMT
============================
TCGA-COAD HCAR1
[1] 286
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.34 0.415 1.11
strata=LOW 12 5 3.66 0.492 1.11
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7892 2.2016 0.7693 1.026 0.305
Likelihood ratio test=1.07 on 1 df, p=0.302
n= 24, number of events= 8
============================
TCGA-COAD HILPDA
[1] 287
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.45 0.0449 0.0904
strata=LOW 12 6 5.55 0.0360 0.0904
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2031 1.2252 0.6766 0.3 0.764
Likelihood ratio test=0.09 on 1 df, p=0.7634
n= 24, number of events= 10
============================
TCGA-COAD GSTM1
[1] 288
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.43 0.0944 0.222
strata=LOW 12 3 3.57 0.0907 0.222
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4063 0.6661 0.8685 -0.468 0.64
Likelihood ratio test=0.23 on 1 df, p=0.6334
n= 24, number of events= 7
============================
TCGA-COAD MIR222
============================
TCGA-COAD RARRES2
[1] 289
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.71 0.611 1.12
strata=LOW 12 3 4.29 0.386 1.12
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8880 0.4115 0.8673 -1.024 0.306
Likelihood ratio test=1.12 on 1 df, p=0.2894
n= 24, number of events= 7
============================
TCGA-COAD BRD4
[1] 290
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.42 0.242 0.459
strata=LOW 12 1 1.58 0.216 0.459
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8082 0.4457 1.2259 -0.659 0.51
Likelihood ratio test=0.46 on 1 df, p=0.4959
n= 24, number of events= 3
============================
TCGA-COAD SOCS1
[1] 291
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.09 0.268 0.76
strata=LOW 12 1 1.91 0.433 0.76
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9682 0.3798 1.1479 -0.843 0.399
Likelihood ratio test=0.83 on 1 df, p=0.3628
n= 24, number of events= 5
============================
TCGA-COAD MIR17
============================
TCGA-COAD GDF15
[1] 292
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.6 0.748 1.37
strata=LOW 12 3 4.4 0.443 1.37
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0037 0.3665 0.8878 -1.131 0.258
Likelihood ratio test=1.38 on 1 df, p=0.2409
n= 24, number of events= 7
============================
TCGA-COAD ARF6
[1] 293
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.91 0.212 0.702
strata=LOW 12 3 2.09 0.396 0.702
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7617 2.1419 0.9294 0.82 0.412
Likelihood ratio test=0.69 on 1 df, p=0.4058
n= 24, number of events= 6
============================
TCGA-COAD CDO1
[1] 294
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.93 0.290 0.767
strata=LOW 12 2 3.07 0.372 0.767
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7442 0.4751 0.8692 -0.856 0.392
Likelihood ratio test=0.78 on 1 df, p=0.3773
n= 24, number of events= 7
============================
TCGA-COAD CAMKK2
[1] 295
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.61 0.143 0.306
strata=LOW 12 3 2.39 0.156 0.306
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5056 1.6581 0.9235 0.548 0.584
Likelihood ratio test=0.31 on 1 df, p=0.5796
n= 24, number of events= 5
============================
TCGA-COAD LINC01606
[1] 296
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.25 1.36 1.9
strata=LOW 30 7 8.75 0.35 1.9
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9410 0.3902 0.7083 -1.329 0.184
Likelihood ratio test=1.7 on 1 df, p=0.1917
n= 42, number of events= 11
============================
TCGA-COAD BACH1
[1] 297
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.72 0.797 2.46
strata=LOW 12 4 2.28 1.302 2.46
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.605 4.979 1.128 1.423 0.155
Likelihood ratio test=2.57 on 1 df, p=0.1088
n= 24, number of events= 6
============================
TCGA-COAD DPP4
[1] 298
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 5.05 0.000465 0.00107
strata=LOW 12 5 4.95 0.000474 0.00107
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02212 1.02237 0.67619 0.033 0.974
Likelihood ratio test=0 on 1 df, p=0.9739
n= 24, number of events= 10
============================
TCGA-COAD PPP1R13L
[1] 299
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 4.73 0.339 0.952
strata=LOW 12 2 3.27 0.491 0.952
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8049 0.4471 0.8460 -0.951 0.341
Likelihood ratio test=0.99 on 1 df, p=0.3203
n= 24, number of events= 8
============================
TCGA-COAD MIR150
============================
TCGA-COAD FLT3
[1] 300
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.77 0.550 1.02
strata=LOW 12 4 5.23 0.291 1.02
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8525 0.4263 0.8675 -0.983 0.326
Likelihood ratio test=1.03 on 1 df, p=0.3096
n= 24, number of events= 8
============================
TCGA-COAD MAP1LC3A
[1] 301
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.11 1.149 2.39
strata=LOW 12 2 3.89 0.919 2.39
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5408 0.2142 1.0965 -1.405 0.16
Likelihood ratio test=2.64 on 1 df, p=0.1045
n= 24, number of events= 7
============================
TCGA-COAD A2M-AS1
[1] 302
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.19 0.0119 0.0256
strata=LOW 12 3 2.81 0.0135 0.0256
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1309 1.1399 0.8190 0.16 0.873
Likelihood ratio test=0.03 on 1 df, p=0.873
n= 24, number of events= 6
============================
TCGA-COAD PDSS2
[1] 303
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.6 0.1396 0.232
strata=LOW 12 6 5.4 0.0673 0.232
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4069 1.5021 0.8510 0.478 0.633
Likelihood ratio test=0.24 on 1 df, p=0.6242
n= 24, number of events= 8
============================
TCGA-COAD DNAJB6
[1] 304
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.68 0.126 0.331
strata=LOW 12 4 3.32 0.140 0.331
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4701 1.6001 0.8238 0.571 0.568
Likelihood ratio test=0.32 on 1 df, p=0.57
n= 24, number of events= 7
============================
TCGA-COAD SUV39H1
[1] 305
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.64 0.157 0.561
strata=LOW 12 2 1.36 0.306 0.561
Chisq= 0.6 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8901 2.4353 1.2276 0.725 0.468
Likelihood ratio test=0.56 on 1 df, p=0.4531
n= 24, number of events= 4
============================
TCGA-COAD LPCAT3
[1] 306
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.69 0.0562 0.136
strata=LOW 12 2 2.31 0.0412 0.136
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4616 0.6303 1.2588 -0.367 0.714
Likelihood ratio test=0.14 on 1 df, p=0.7083
n= 24, number of events= 4
============================
TCGA-COAD MIR761
============================
TCGA-COAD CDCA3
[1] 307
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.8 0.0221 0.0828
strata=LOW 12 1 1.2 0.0331 0.0828
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4043 0.6674 1.4146 -0.286 0.775
Likelihood ratio test=0.08 on 1 df, p=0.7758
n= 24, number of events= 3
============================
TCGA-COAD EPAS1
[1] 308
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.11 1.684 2.68
strata=LOW 12 2 3.89 0.916 2.68
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3501 0.2592 0.8818 -1.531 0.126
Likelihood ratio test=2.53 on 1 df, p=0.1114
n= 24, number of events= 6
============================
TCGA-COAD SLC11A2
[1] 309
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.19 0.646 1.43
strata=LOW 12 3 1.81 0.780 1.43
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.295 3.651 1.157 1.119 0.263
Likelihood ratio test=1.47 on 1 df, p=0.2254
n= 24, number of events= 4
============================
TCGA-COAD CREB3
[1] 310
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 0.967 1.105 2.14
strata=LOW 12 2 3.033 0.352 2.14
Chisq= 2.1 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.127e+01 5.763e-10 2.846e+04 -0.001 0.999
Likelihood ratio test=2.91 on 1 df, p=0.088
n= 24, number of events= 4
============================
TCGA-COAD ATF3
[1] 311
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.27 0.163 0.363
strata=LOW 12 3 3.73 0.143 0.363
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5192 0.5950 0.8713 -0.596 0.551
Likelihood ratio test=0.37 on 1 df, p=0.5419
n= 24, number of events= 7
============================
TCGA-COAD TGFB1
[1] 312
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.91 0.615 1.02
strata=LOW 12 2 3.09 0.382 1.02
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9040 0.4050 0.9244 -0.978 0.328
Likelihood ratio test=0.98 on 1 df, p=0.3214
n= 24, number of events= 5
============================
TCGA-COAD SMG9
[1] 313
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.16 0.00601 0.0253
strata=LOW 12 2 1.84 0.01356 0.0253
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1597 1.1732 1.0041 0.159 0.874
Likelihood ratio test=0.03 on 1 df, p=0.8737
n= 24, number of events= 6
============================
TCGA-COAD NOX4
[1] 314
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.06 0.218 0.528
strata=LOW 12 2 2.94 0.301 0.528
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6029 0.5472 0.8419 -0.716 0.474
Likelihood ratio test=0.55 on 1 df, p=0.4578
n= 24, number of events= 7
============================
TCGA-COAD MIR27A
============================
TCGA-COAD FOXP1
[1] 315
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.15 0.0101 0.0219
strata=LOW 12 2 1.85 0.0117 0.0219
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1481 1.1596 1.0012 0.148 0.882
Likelihood ratio test=0.02 on 1 df, p=0.8825
n= 24, number of events= 4
============================
TCGA-COAD SNCA
[1] 316
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 1.75 2.91 5.42
strata=LOW 12 0 2.25 2.25 5.42
Chisq= 5.4 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.166e+01 3.921e-10 2.057e+04 -0.001 0.999
Likelihood ratio test=6.95 on 1 df, p=0.008381
n= 24, number of events= 4
============================
TCGA-COAD ENPP2
[1] 317
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.9 0.415 0.83
strata=LOW 12 4 5.1 0.236 0.83
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7803 0.4583 0.8769 -0.89 0.374
Likelihood ratio test=0.84 on 1 df, p=0.3592
n= 24, number of events= 8
============================
TCGA-COAD BRD2
[1] 318
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.85 0.0119 0.0254
strata=LOW 12 2 2.15 0.0103 0.0254
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1697 0.8439 1.0660 -0.159 0.873
Likelihood ratio test=0.03 on 1 df, p=0.8737
n= 24, number of events= 4
============================
TCGA-COAD ISCU
[1] 319
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.89 0.00456 0.0112
strata=LOW 12 2 2.11 0.00622 0.0112
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.09869 0.90602 0.93161 -0.106 0.916
Likelihood ratio test=0.01 on 1 df, p=0.9154
n= 24, number of events= 5
============================
TCGA-COAD PHF21A
[1] 320
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 2.82 1.7 3.28
strata=LOW 12 1 3.18 1.5 3.28
Chisq= 3.3 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7715 0.1701 1.1038 -1.605 0.109
Likelihood ratio test=3.51 on 1 df, p=0.06096
n= 24, number of events= 6
============================
TCGA-COAD PARP6
[1] 321
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.03 0.915 1.89
strata=LOW 12 1 1.97 0.478 1.89
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.115e+01 6.542e-10 2.845e+04 -0.001 0.999
Likelihood ratio test=2.66 on 1 df, p=0.103
n= 24, number of events= 3
============================
TCGA-COAD ZEB1
[1] 322
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.34 0.0353 0.0799
strata=LOW 12 4 3.66 0.0323 0.0799
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2306 1.2594 0.8175 0.282 0.778
Likelihood ratio test=0.08 on 1 df, p=0.7781
n= 24, number of events= 7
============================
TCGA-COAD LIG3
[1] 323
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.12 0.00660 0.0141
strata=LOW 12 3 2.88 0.00485 0.0141
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1186 1.1259 1.0010 0.118 0.906
Likelihood ratio test=0.01 on 1 df, p=0.9057
n= 24, number of events= 5
============================
TCGA-COAD PEDS1
[1] 324
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.03 0.464 0.956
strata=LOW 12 2 2.97 0.317 0.956
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0830 0.3386 1.1608 -0.933 0.351
Likelihood ratio test=1 on 1 df, p=0.3169
n= 24, number of events= 5
============================
TCGA-COAD RPPH1
============================
TCGA-COAD GFRA1
[1] 325
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.31 0.517 1.2
strata=LOW 12 5 3.69 0.463 1.2
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9314 2.5381 0.8783 1.06 0.289
Likelihood ratio test=1.2 on 1 df, p=0.2735
n= 24, number of events= 7
============================
TCGA-COAD AQP8
[1] 326
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.78 0.344 0.639
strata=LOW 12 4 3.22 0.191 0.639
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9032 2.4676 1.1665 0.774 0.439
Likelihood ratio test=0.68 on 1 df, p=0.4109
n= 24, number of events= 5
============================
TCGA-COAD SIRT1
[1] 327
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.06 0.365 1.17
strata=LOW 12 3 1.94 0.574 1.17
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.197 3.311 1.170 1.024 0.306
Likelihood ratio test=1.21 on 1 df, p=0.2715
n= 24, number of events= 5
============================
TCGA-COAD MIR15A
============================
TCGA-COAD AKR1C3
[1] 328
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.1 0.00323 0.0067
strata=LOW 12 4 3.9 0.00257 0.0067
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.06687 1.06915 0.81707 0.082 0.935
Likelihood ratio test=0.01 on 1 df, p=0.9348
n= 24, number of events= 7
============================
TCGA-COAD DLD
[1] 329
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.18 0.01428 0.0264
strata=LOW 12 4 3.82 0.00813 0.0264
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1513 1.1634 0.9318 0.162 0.871
Likelihood ratio test=0.03 on 1 df, p=0.8705
n= 24, number of events= 6
============================
TCGA-COAD USP11
[1] 330
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.88 0.667 1.8
strata=LOW 12 1 2.12 0.592 1.8
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.079e+01 9.376e-10 2.434e+04 -0.001 0.999
Likelihood ratio test=2.81 on 1 df, p=0.09355
n= 24, number of events= 4
============================
TCGA-COAD SREBF2
[1] 331
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.44 0.992 1.58
strata=LOW 12 3 4.56 0.532 1.58
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9475 0.3877 0.7791 -1.216 0.224
Likelihood ratio test=1.49 on 1 df, p=0.2218
n= 24, number of events= 7
============================
TCGA-COAD MIR190A
============================
TCGA-COAD IFNA8
============================
TCGA-COAD KDM6B
[1] 332
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 1.84 2.52 4.01
strata=LOW 12 1 3.16 1.47 4.01
Chisq= 4 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.9287 0.1453 1.1190 -1.724 0.0848
Likelihood ratio test=3.91 on 1 df, p=0.04806
n= 24, number of events= 5
============================
TCGA-COAD ACOT1
[1] 333
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.45 0.472 2.38
strata=LOW 12 3 1.55 1.355 2.38
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.674 5.334 1.189 1.408 0.159
Likelihood ratio test=2.34 on 1 df, p=0.1261
n= 24, number of events= 6
============================
TCGA-COAD RELA
[1] 334
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.55 1.36 2.81
strata=LOW 12 0 1.45 1.45 2.81
Chisq= 2.8 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.114e+01 6.597e-10 2.323e+04 -0.001 0.999
Likelihood ratio test=3.96 on 1 df, p=0.0465
n= 24, number of events= 3
============================
TCGA-COAD SLC39A7
[1] 335
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.76 0.0318 0.0614
strata=LOW 12 2 2.24 0.0251 0.0614
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2565 0.7737 1.0374 -0.247 0.805
Likelihood ratio test=0.06 on 1 df, p=0.8051
n= 24, number of events= 4
============================
TCGA-COAD POM121L12
============================
TCGA-COAD MIR101-1
============================
TCGA-COAD GABPB1-AS1
[1] 336
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.45 0.0843 0.144
strata=LOW 12 5 4.55 0.0455 0.144
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3295 1.3903 0.8709 0.378 0.705
Likelihood ratio test=0.15 on 1 df, p=0.7006
n= 24, number of events= 7
============================
TCGA-COAD EGFR
[1] 337
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.05 0.536 1.12
strata=LOW 12 3 1.95 0.562 1.12
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.163 3.200 1.161 1.002 0.316
Likelihood ratio test=1.16 on 1 df, p=0.281
n= 24, number of events= 4
============================
TCGA-COAD BRD7
[1] 338
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.39 0.0446 0.0807
strata=LOW 12 5 4.61 0.0328 0.0807
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2111 1.2351 0.7442 0.284 0.777
Likelihood ratio test=0.08 on 1 df, p=0.7751
n= 24, number of events= 8
============================
TCGA-COAD MIR1287
============================
TCGA-COAD MIR23A
============================
TCGA-COAD LCE2C
============================
TCGA-COAD ADAMTS13
[1] 339
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.67 0.668 1.12
strata=LOW 12 3 4.33 0.411 1.12
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8011 0.4488 0.7754 -1.033 0.302
Likelihood ratio test=1.08 on 1 df, p=0.2993
n= 24, number of events= 7
============================
TCGA-COAD SIRT3
[1] 340
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.44 0.128 0.259
strata=LOW 12 2 2.56 0.122 0.259
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4680 0.6263 0.9276 -0.504 0.614
Likelihood ratio test=0.26 on 1 df, p=0.61
n= 24, number of events= 5
============================
TCGA-COAD CIRBP
[1] 341
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.34 1.180 1.96
strata=LOW 12 2 3.66 0.754 1.96
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1539 0.3154 0.8701 -1.326 0.185
Likelihood ratio test=1.9 on 1 df, p=0.1685
n= 24, number of events= 6
============================
TCGA-COAD BRDT
============================
TCGA-COAD KIF4A
[1] 342
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.17 0.330 1.4
strata=LOW 12 3 1.83 0.754 1.4
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.280 3.595 1.157 1.106 0.269
Likelihood ratio test=1.43 on 1 df, p=0.2312
n= 24, number of events= 6
============================
TCGA-COAD CPEB1
[1] 343
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.9 0.421 0.819
strata=LOW 12 2 3.1 0.393 0.819
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7668 0.4645 0.8680 -0.883 0.377
Likelihood ratio test=0.83 on 1 df, p=0.3621
n= 24, number of events= 6
============================
TCGA-COAD LINC01833
[1] 344
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.55 0.0665 0.154
strata=LOW 14 5 4.45 0.0681 0.154
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2864 1.3317 0.7321 0.391 0.696
Likelihood ratio test=0.16 on 1 df, p=0.6926
n= 26, number of events= 9
============================
TCGA-COAD MAPKAP1
[1] 345
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 4.11 0.301 0.641
strata=LOW 12 5 3.89 0.319 0.641
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5850 1.7950 0.7404 0.79 0.429
Likelihood ratio test=0.65 on 1 df, p=0.4219
n= 24, number of events= 8
============================
TCGA-COAD ATF4
[1] 346
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.89 0.319 0.883
strata=LOW 12 2 3.11 0.398 0.883
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8109 0.4445 0.8844 -0.917 0.359
Likelihood ratio test=0.89 on 1 df, p=0.3457
n= 24, number of events= 7
============================
TCGA-COAD SLC7A11
[1] 347
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.81 0.0131 0.0254
strata=LOW 12 3 3.19 0.0116 0.0254
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1322 0.8762 0.8293 -0.159 0.873
Likelihood ratio test=0.03 on 1 df, p=0.8734
n= 24, number of events= 6
============================
TCGA-COAD EMC2
[1] 348
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.55 0.195 0.405
strata=LOW 12 2 1.45 0.209 0.405
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7615 2.1415 1.2260 0.621 0.535
Likelihood ratio test=0.41 on 1 df, p=0.5216
n= 24, number of events= 3
============================
TCGA-COAD WWTR1
[1] 349
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.47 0.114 0.225
strata=LOW 12 2 2.53 0.111 0.225
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4305 0.6502 0.9137 -0.471 0.638
Likelihood ratio test=0.23 on 1 df, p=0.634
n= 24, number of events= 5
============================
TCGA-COAD HSPA5
[1] 350
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 1.29 5.67 8.16
strata=LOW 12 2 4.71 1.56 8.16
Chisq= 8.2 on 1 degrees of freedom, p= 0.004
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.65741 0.07013 1.15593 -2.299 0.0215
Likelihood ratio test=6.98 on 1 df, p=0.008225
n= 24, number of events= 6
============================
TCGA-COAD BEX1
[1] 351
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.95 0.566 1.24
strata=LOW 12 2 3.05 0.362 1.24
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3181 0.2676 1.2362 -1.066 0.286
Likelihood ratio test=1.31 on 1 df, p=0.2515
n= 24, number of events= 5
============================
TCGA-COAD PML
[1] 352
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.87 0.681 2.59
strata=LOW 12 0 1.13 1.129 2.59
Chisq= 2.6 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.149e+01 4.624e-10 2.885e+04 -0.001 0.999
Likelihood ratio test=3.33 on 1 df, p=0.06815
n= 24, number of events= 3
============================
TCGA-COAD MIR142
============================
TCGA-COAD AEBP2
[1] 353
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.56 0.121 0.413
strata=LOW 12 2 1.44 0.214 0.413
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.768 2.155 1.225 0.627 0.531
Likelihood ratio test=0.42 on 1 df, p=0.5177
n= 24, number of events= 4
============================
TCGA-COAD GPAT4
[1] 354
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.72 0.192 0.455
strata=LOW 12 4 3.28 0.159 0.455
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6336 1.8844 0.9515 0.666 0.505
Likelihood ratio test=0.45 on 1 df, p=0.5001
n= 24, number of events= 6
============================
TCGA-COAD CA9
[1] 355
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.15 0.0109 0.0242
strata=LOW 12 2 1.85 0.0126 0.0242
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1578 1.1709 1.0152 0.155 0.876
Likelihood ratio test=0.02 on 1 df, p=0.8765
n= 24, number of events= 4
============================
TCGA-COAD STK11
[1] 356
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.85 0.00605 0.0136
strata=LOW 12 4 4.15 0.00560 0.0136
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.08947 0.91442 0.76800 -0.116 0.907
Likelihood ratio test=0.01 on 1 df, p=0.9071
n= 24, number of events= 8
============================
TCGA-COAD TBK1
[1] 357
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.87 0.904 2.89
strata=LOW 12 4 2.13 1.642 2.89
Chisq= 2.9 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.697 5.459 1.121 1.514 0.13
Likelihood ratio test=2.96 on 1 df, p=0.08549
n= 24, number of events= 6
============================
TCGA-COAD CDKN2A
[1] 358
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.63 0.707 1.5
strata=LOW 12 2 3.37 0.554 1.5
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2807 0.2778 1.1188 -1.145 0.252
Likelihood ratio test=1.62 on 1 df, p=0.2029
n= 24, number of events= 6
============================
TCGA-COAD DCAF7
[1] 359
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.64 0.248 0.547
strata=LOW 12 2 1.36 0.298 0.547
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8774 2.4048 1.2251 0.716 0.474
Likelihood ratio test=0.55 on 1 df, p=0.4587
n= 24, number of events= 3
============================
TCGA-COAD MTF1
[1] 360
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.5 0.0724 0.203
strata=LOW 12 2 2.5 0.1011 0.203
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4084 0.6647 0.9134 -0.447 0.655
Likelihood ratio test=0.2 on 1 df, p=0.6514
n= 24, number of events= 6
============================
TCGA-COAD MEG8
[1] 361
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.27 0.235 0.451
strata=LOW 12 4 4.73 0.113 0.451
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6205 0.5377 0.9371 -0.662 0.508
Likelihood ratio test=0.45 on 1 df, p=0.5021
n= 24, number of events= 7
============================
TCGA-COAD CLTRN
[1] 362
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.17 0.594 1.43
strata=LOW 12 1 1.83 0.378 1.43
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.991e+01 2.262e-09 1.760e+04 -0.001 0.999
Likelihood ratio test=2.15 on 1 df, p=0.1422
n= 24, number of events= 3
============================
TCGA-COAD PARP11
[1] 363
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.97 0.000230 0.000576
strata=LOW 12 4 4.03 0.000284 0.000576
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.01704 0.98311 0.70961 -0.024 0.981
Likelihood ratio test=0 on 1 df, p=0.9808
n= 24, number of events= 9
============================
TCGA-COAD GABARAPL2
[1] 364
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.83 0.742 1.4
strata=LOW 12 1 2.17 0.628 1.4
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2936 0.2743 1.1660 -1.109 0.267
Likelihood ratio test=1.44 on 1 df, p=0.2301
n= 24, number of events= 4
============================
TCGA-COAD CDKN1A
[1] 365
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.22 0.0212 0.0393
strata=LOW 12 3 2.78 0.0169 0.0393
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1834 1.2013 0.9259 0.198 0.843
Likelihood ratio test=0.04 on 1 df, p=0.8422
n= 24, number of events= 5
============================
TCGA-COAD NEDD4L
[1] 366
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.97 0.981 1.96
strata=LOW 12 7 5.03 0.776 1.96
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.091 2.977 0.818 1.333 0.182
Likelihood ratio test=2.05 on 1 df, p=0.152
n= 24, number of events= 9
============================
TCGA-COAD AR
[1] 367
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.45 0.0890 0.178
strata=LOW 12 3 3.55 0.0863 0.178
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3243 0.7230 0.7710 -0.421 0.674
Likelihood ratio test=0.18 on 1 df, p=0.6723
n= 24, number of events= 7
============================
TCGA-COAD MIR20A
============================
TCGA-COAD HMOX1
[1] 368
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.56 0.0550 0.169
strata=LOW 12 2 2.44 0.0801 0.169
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3849 0.6805 0.9417 -0.409 0.683
Likelihood ratio test=0.17 on 1 df, p=0.6806
n= 24, number of events= 6
============================
TCGA-COAD ZFP36
[1] 369
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.82 0.00826 0.026
strata=LOW 12 2 2.18 0.01449 0.026
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1478 0.8626 0.9178 -0.161 0.872
Likelihood ratio test=0.03 on 1 df, p=0.8715
n= 24, number of events= 6
============================
TCGA-COAD MIR744
============================
TCGA-COAD CTSB
[1] 370
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.98 0.259 0.626
strata=LOW 12 3 4.02 0.257 0.626
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6061 0.5455 0.7765 -0.78 0.435
Likelihood ratio test=0.62 on 1 df, p=0.4324
n= 24, number of events= 8
============================
TCGA-COAD AGPS
[1] 371
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.22 0.0150 0.0397
strata=LOW 12 3 2.78 0.0174 0.0397
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1831 1.2010 0.9199 0.199 0.842
Likelihood ratio test=0.04 on 1 df, p=0.8414
n= 24, number of events= 6
============================
TCGA-COAD MT1DP
[1] 372
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.46 0.0855 0.326
strata=LOW 12 2 1.54 0.1363 0.326
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7468 2.1102 1.3249 0.564 0.573
Likelihood ratio test=0.34 on 1 df, p=0.5626
n= 24, number of events= 4
============================
TCGA-COAD SNX4
[1] 373
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.33 0.0475 0.114
strata=LOW 12 3 2.67 0.0416 0.114
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3364 1.3999 1.0006 0.336 0.737
Likelihood ratio test=0.11 on 1 df, p=0.7373
n= 24, number of events= 5
============================
TCGA-COAD NR4A1
[1] 374
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.75 0.571 1.27
strata=LOW 12 3 4.25 0.369 1.27
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1923 0.3035 1.1197 -1.065 0.287
Likelihood ratio test=1.39 on 1 df, p=0.239
n= 24, number of events= 7
============================
TCGA-COAD MFN2
[1] 375
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.44 0.0897 0.413
strata=LOW 12 1 1.56 0.1985 0.413
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7680 0.4639 1.2251 -0.627 0.531
Likelihood ratio test=0.42 on 1 df, p=0.5177
n= 24, number of events= 5
============================
TCGA-COAD SELENOI
[1] 376
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.51 0.1037 0.212
strata=LOW 12 4 3.49 0.0746 0.212
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4202 1.5223 0.9197 0.457 0.648
Likelihood ratio test=0.21 on 1 df, p=0.6445
n= 24, number of events= 6
============================
TCGA-COAD AGAP2-AS1
[1] 377
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.15 1.6 2.82
strata=LOW 12 1 2.85 1.2 2.82
Chisq= 2.8 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.6803 0.1863 1.1205 -1.5 0.134
Likelihood ratio test=2.9 on 1 df, p=0.0887
n= 24, number of events= 5
============================
TCGA-COAD TRIM46
[1] 378
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.84 0.732 1.16
strata=LOW 12 2 3.16 0.426 1.16
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9504 0.3866 0.9146 -1.039 0.299
Likelihood ratio test=1.11 on 1 df, p=0.2923
n= 24, number of events= 5
============================
TCGA-COAD CYB5R1
[1] 379
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.71 0.0489 0.0856
strata=LOW 12 3 3.29 0.0254 0.0856
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2919 0.7468 1.0011 -0.292 0.771
Likelihood ratio test=0.08 on 1 df, p=0.771
n= 24, number of events= 5
============================
TCGA-COAD PARK7
[1] 380
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.18 0.0142 0.0432
strata=LOW 12 2 1.82 0.0169 0.0432
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.254 1.289 1.225 0.207 0.836
Likelihood ratio test=0.04 on 1 df, p=0.8337
n= 24, number of events= 4
============================
TCGA-COAD CARS1
[1] 381
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 5.43 0.0595 0.314
strata=LOW 12 1 1.57 0.2061 0.314
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6252 0.5351 1.1336 -0.552 0.581
Likelihood ratio test=0.34 on 1 df, p=0.5604
n= 24, number of events= 7
============================
TCGA-COAD NOX1
[1] 382
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 2.212 2.21 8.91
strata=LOW 12 3 0.788 6.22 8.91
Chisq= 8.9 on 1 degrees of freedom, p= 0.003
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.316e+01 1.147e+10 3.212e+04 0.001 0.999
Likelihood ratio test=8.6 on 1 df, p=0.003355
n= 24, number of events= 3
============================
TCGA-COAD VDR
[1] 383
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.24 0.0183 0.0482
strata=LOW 12 3 2.76 0.0215 0.0482
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2004 1.2219 0.9144 0.219 0.827
Likelihood ratio test=0.05 on 1 df, p=0.8255
n= 24, number of events= 6
============================
TCGA-COAD PROK2
[1] 384
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.38 0.115 0.231
strata=LOW 12 3 3.62 0.107 0.231
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3718 0.6895 0.7778 -0.478 0.633
Likelihood ratio test=0.23 on 1 df, p=0.6308
n= 24, number of events= 7
============================
TCGA-COAD FABP4
[1] 385
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.8 0.00868 0.0275
strata=LOW 12 3 3.2 0.01300 0.0275
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1361 0.8728 0.8206 -0.166 0.868
Likelihood ratio test=0.03 on 1 df, p=0.8679
n= 24, number of events= 8
============================
TCGA-COAD ABCB10
[1] 386
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.99 1.32 2.7
strata=LOW 12 5 3.01 1.31 2.7
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.629 5.098 1.101 1.48 0.139
Likelihood ratio test=2.94 on 1 df, p=0.08652
n= 24, number of events= 6
============================
TCGA-COAD CP
[1] 387
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.55 0.0863 0.214
strata=LOW 12 3 2.45 0.1254 0.214
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3780 1.4593 0.8214 0.46 0.645
Likelihood ratio test=0.21 on 1 df, p=0.6464
n= 24, number of events= 6
============================
TCGA-COAD MIR4735
============================
TCGA-COAD MIR130A
============================
TCGA-COAD TUG1
[1] 388
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.77 0.216 0.409
strata=LOW 12 4 3.23 0.186 0.409
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5508 1.7346 0.8718 0.632 0.528
Likelihood ratio test=0.42 on 1 df, p=0.5175
n= 24, number of events= 6
============================
TCGA-COAD MIR9-3HG
[1] 389
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.59 0.0755 0.203
strata=LOW 12 4 3.41 0.1016 0.203
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3474 1.4154 0.7743 0.449 0.654
Likelihood ratio test=0.2 on 1 df, p=0.6517
n= 24, number of events= 8
============================
TCGA-COAD MIR196C
============================
TCGA-COAD IFNA21
============================
TCGA-COAD RP11-274B21.9
[1] 390
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.36 0.0383 0.0894
strata=LOW 12 3 2.64 0.0487 0.0894
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2470 1.2802 0.8279 0.298 0.765
Likelihood ratio test=0.09 on 1 df, p=0.7657
n= 24, number of events= 6
============================
TCGA-COAD PVT1
[1] 391
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.2 2.68 4.53
strata=LOW 12 1 2.8 1.15 4.53
Chisq= 4.5 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.172e+01 3.695e-10 2.419e+04 -0.001 0.999
Likelihood ratio test=5.54 on 1 df, p=0.01861
n= 24, number of events= 4
============================
TCGA-COAD MIR539
============================
TCGA-COAD IFNA2
============================
TCGA-COAD TFRC
[1] 392
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.056 0.542 2.24
strata=LOW 12 2 0.944 1.180 2.24
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.133e+01 1.830e+09 2.852e+04 0.001 0.999
Likelihood ratio test=3.01 on 1 df, p=0.08285
n= 24, number of events= 3
============================
TCGA-COAD ALOX15B
[1] 393
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.84 0.350 1.18
strata=LOW 12 2 3.16 0.425 1.18
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9676 0.3800 0.9229 -1.049 0.294
Likelihood ratio test=1.13 on 1 df, p=0.2883
n= 24, number of events= 7
============================
TCGA-COAD MPC1
[1] 394
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.97 0.000246 0.000611
strata=LOW 12 2 2.03 0.000361 0.000611
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.02263 0.97762 0.91583 -0.025 0.98
Likelihood ratio test=0 on 1 df, p=0.9803
n= 24, number of events= 5
============================
TCGA-COAD MTCH1
[1] 395
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.35 0.0373 0.0732
strata=LOW 12 5 4.65 0.0269 0.0732
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2084 1.2317 0.7717 0.27 0.787
Likelihood ratio test=0.07 on 1 df, p=0.7863
n= 24, number of events= 8
============================
TCGA-COAD MIR324
============================
TCGA-COAD SNHG14
[1] 396
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.67 0.0413 0.0769
strata=LOW 12 5 5.33 0.0207 0.0769
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2301 0.7945 0.8315 -0.277 0.782
Likelihood ratio test=0.08 on 1 df, p=0.7821
n= 24, number of events= 8
============================
TCGA-COAD PDK4
[1] 397
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.67 0.167 0.366
strata=LOW 12 3 2.33 0.191 0.366
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5528 1.7381 0.9242 0.598 0.55
Likelihood ratio test=0.37 on 1 df, p=0.5449
n= 24, number of events= 5
============================
TCGA-COAD DUOX1
[1] 398
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.83 0.241 0.457
strata=LOW 12 4 3.17 0.214 0.457
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5788 1.7838 0.8676 0.667 0.505
Likelihood ratio test=0.47 on 1 df, p=0.4936
n= 24, number of events= 6
============================
TCGA-COAD LINC00886
[1] 399
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.4 0.575 1.12
strata=LOW 12 6 4.6 0.425 1.12
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8610 2.3655 0.8379 1.028 0.304
Likelihood ratio test=1.16 on 1 df, p=0.2807
n= 24, number of events= 8
============================
TCGA-COAD NF2
[1] 400
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.58 0.0926 0.19
strata=LOW 12 4 3.42 0.0967 0.19
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3319 1.3937 0.7651 0.434 0.664
Likelihood ratio test=0.19 on 1 df, p=0.6626
n= 24, number of events= 7
============================
TCGA-COAD MIR149
============================
TCGA-COAD CYP4F8
[1] 401
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.5 0.0545 0.129
strata=LOW 12 4 3.5 0.0699 0.129
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2580 1.2944 0.7197 0.359 0.72
Likelihood ratio test=0.13 on 1 df, p=0.7204
n= 24, number of events= 8
============================
TCGA-COAD AKR1C1
[1] 402
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.66 0.670 1.44
strata=LOW 12 2 3.34 0.535 1.44
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2591 0.2839 1.1194 -1.125 0.261
Likelihood ratio test=1.56 on 1 df, p=0.2116
n= 24, number of events= 6
============================
TCGA-COAD PRKCA
[1] 403
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 4.32 1.24 3.66
strata=LOW 12 5 2.68 2.01 3.66
Chisq= 3.7 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.836 6.270 1.098 1.672 0.0945
Likelihood ratio test=3.86 on 1 df, p=0.04938
n= 24, number of events= 7
============================
TCGA-COAD CD44
[1] 404
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 1.8 0.0213 0.0571
strata=LOW 12 1 1.2 0.0321 0.0571
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3004 0.7405 1.2613 -0.238 0.812
Likelihood ratio test=0.06 on 1 df, p=0.8094
n= 24, number of events= 3
============================
TCGA-COAD FBXW7
[1] 405
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.59 0.705 1.77
strata=LOW 12 4 2.41 1.051 1.77
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.104 3.015 0.870 1.269 0.205
Likelihood ratio test=1.73 on 1 df, p=0.1879
n= 24, number of events= 6
============================
TCGA-COAD YAP1
[1] 406
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 2.92 2.92 7.32
strata=LOW 12 5 2.08 4.12 7.32
Chisq= 7.3 on 1 degrees of freedom, p= 0.007
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.170e+01 2.668e+09 1.877e+04 0.001 0.999
Likelihood ratio test=9.02 on 1 df, p=0.002666
n= 24, number of events= 5
============================
TCGA-COAD MTOR
[1] 407
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.96 0.232 0.613
strata=LOW 12 4 3.04 0.301 0.613
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6663 1.9471 0.8669 0.769 0.442
Likelihood ratio test=0.63 on 1 df, p=0.4289
n= 24, number of events= 7
============================
TCGA-COAD RICTOR
[1] 408
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.97 0.314 0.964
strata=LOW 12 3 2.03 0.458 0.964
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.094 2.987 1.167 0.938 0.348
Likelihood ratio test=1.01 on 1 df, p=0.3153
n= 24, number of events= 5
============================
TCGA-COAD WIPI2
[1] 409
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.17 0.215 0.478
strata=LOW 12 2 2.83 0.241 0.478
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6016 0.5479 0.8817 -0.682 0.495
Likelihood ratio test=0.49 on 1 df, p=0.4846
n= 24, number of events= 6
============================
TCGA-COAD IREB2
[1] 410
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.74 1.74 4.15
strata=LOW 12 4 2.26 1.34 4.15
Chisq= 4.2 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.158e+01 2.357e+09 2.378e+04 0.001 0.999
Likelihood ratio test=5.22 on 1 df, p=0.02238
n= 24, number of events= 4
============================
TCGA-COAD GOT1
[1] 411
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 4.08 0.00171 0.00616
strata=LOW 12 3 2.92 0.00239 0.00616
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.0742 1.0770 0.9459 0.078 0.937
Likelihood ratio test=0.01 on 1 df, p=0.9373
n= 24, number of events= 7
============================
TCGA-COAD CD82
[1] 412
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.31 0.859 2.29
strata=LOW 12 1 2.69 1.059 2.29
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5390 0.2146 1.1187 -1.376 0.169
Likelihood ratio test=2.41 on 1 df, p=0.1205
n= 24, number of events= 6
============================
TCGA-COAD MAPK9
[1] 413
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 4.77 2.98 10.2
strata=LOW 12 6 2.23 6.35 10.2
Chisq= 10.2 on 1 degrees of freedom, p= 0.001
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.190e+01 3.231e+09 1.761e+04 0.001 0.999
Likelihood ratio test=11.97 on 1 df, p=0.0005413
n= 24, number of events= 7
============================
TCGA-COAD LGMN
[1] 414
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.87 0.00606 0.0175
strata=LOW 12 2 2.13 0.00816 0.0175
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1323 0.8761 1.0010 -0.132 0.895
Likelihood ratio test=0.02 on 1 df, p=0.8949
n= 24, number of events= 5
============================
TCGA-COAD PARP2
[1] 415
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.09 0.382 1.2
strata=LOW 12 3 1.91 0.617 1.2
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.203 3.331 1.162 1.035 0.301
Likelihood ratio test=1.25 on 1 df, p=0.2643
n= 24, number of events= 5
============================
TCGA-COAD MIR16-1
============================
TCGA-COAD ATG4D
[1] 416
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.76 0.155 0.393
strata=LOW 12 4 3.24 0.181 0.393
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5369 1.7107 0.8669 0.619 0.536
Likelihood ratio test=0.4 on 1 df, p=0.5257
n= 24, number of events= 7
============================
TCGA-COAD RBMS1
[1] 417
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.57 0.0732 0.151
strata=LOW 12 3 3.43 0.0547 0.151
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3544 0.7016 0.9157 -0.387 0.699
Likelihood ratio test=0.15 on 1 df, p=0.6961
n= 24, number of events= 6
============================
TCGA-COAD GSTZ1
[1] 418
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.67 0.0418 0.116
strata=LOW 12 2 2.33 0.0478 0.116
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3407 0.7113 1.0055 -0.339 0.735
Likelihood ratio test=0.11 on 1 df, p=0.7353
n= 24, number of events= 5
============================
TCGA-COAD SRSF9
[1] 419
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.83 0.00739 0.019
strata=LOW 12 3 3.17 0.00893 0.019
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1125 0.8936 0.8174 -0.138 0.891
Likelihood ratio test=0.02 on 1 df, p=0.8905
n= 24, number of events= 7
============================
TCGA-COAD HIF1A
[1] 420
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 3.59 0.550 1.24
strata=LOW 12 3 4.41 0.449 1.24
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8418 0.4309 0.7755 -1.085 0.278
Likelihood ratio test=1.19 on 1 df, p=0.2748
n= 24, number of events= 8
============================
TCGA-COAD FNDC3B
[1] 421
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.93 0.449 0.881
strata=LOW 12 5 4.07 0.213 0.881
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.044 2.839 1.161 0.899 0.369
Likelihood ratio test=0.93 on 1 df, p=0.3359
n= 24, number of events= 6
============================
TCGA-COAD RHEBP1
============================
TCGA-COAD PSEN1
[1] 422
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.31 0.0283 0.0634
strata=LOW 12 5 4.69 0.0199 0.0634
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2059 1.2286 0.8189 0.251 0.801
Likelihood ratio test=0.06 on 1 df, p=0.8017
n= 24, number of events= 8
============================
TCGA-COAD ADIPOQ
[1] 423
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.65 0.0338 0.0706
strata=LOW 25 5 5.35 0.0231 0.0706
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1953 0.8226 0.7361 -0.265 0.791
Likelihood ratio test=0.07 on 1 df, p=0.7924
n= 37, number of events= 9
============================
TCGA-COAD MUC1
[1] 424
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.28 0.0355 0.0688
strata=LOW 12 3 2.72 0.0299 0.0688
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2453 1.2780 0.9372 0.262 0.793
Likelihood ratio test=0.07 on 1 df, p=0.7921
n= 24, number of events= 5
============================
TCGA-COAD CAV1
[1] 425
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.19 1.485 2.36
strata=LOW 12 4 5.81 0.561 2.36
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2547 0.2852 0.8698 -1.443 0.149
Likelihood ratio test=2.25 on 1 df, p=0.1337
n= 24, number of events= 8
============================
TCGA-COAD SEC24B
[1] 426
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.01 2.35e-05 4.83e-05
strata=LOW 12 3 2.99 1.58e-05 4.83e-05
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.007025 1.007050 1.011117 0.007 0.994
Likelihood ratio test=0 on 1 df, p=0.9945
n= 24, number of events= 5
============================
TCGA-COAD PRDX6
[1] 427
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.98 0.000125 0.000375
strata=LOW 12 2 2.02 0.000185 0.000375
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.01943 0.98076 1.00297 -0.019 0.985
Likelihood ratio test=0 on 1 df, p=0.9845
n= 24, number of events= 5
============================
TCGA-COAD TMEM161B-DT
[1] 428
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 1.85 0.387 0.727
strata=LOW 12 4 3.15 0.227 0.727
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9526 2.5924 1.1589 0.822 0.411
Likelihood ratio test=0.77 on 1 df, p=0.3807
n= 24, number of events= 5
============================
TCGA-COAD PGD
[1] 429
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 5 4.11 0.192 0.814
strata=LOW 12 1 1.89 0.418 0.814
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0097 0.3643 1.1645 -0.867 0.386
Likelihood ratio test=0.86 on 1 df, p=0.3546
n= 24, number of events= 6
============================
TCGA-COAD RHOT1
[1] 430
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.53 0.1117 0.199
strata=LOW 12 4 3.47 0.0815 0.199
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3886 1.4749 0.8765 0.443 0.658
Likelihood ratio test=0.2 on 1 df, p=0.6518
n= 24, number of events= 6
============================
TCGA-COAD ACSL1
[1] 431
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.78 0.0173 0.0394
strata=LOW 12 2 2.22 0.0217 0.0394
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1820 0.8336 0.9176 -0.198 0.843
Likelihood ratio test=0.04 on 1 df, p=0.842
n= 24, number of events= 5
============================
TCGA-COAD NEDD4
[1] 432
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.23 0.469 1.04
strata=LOW 12 5 3.77 0.402 1.04
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8645 2.3739 0.8732 0.99 0.322
Likelihood ratio test=1.05 on 1 df, p=0.3065
n= 24, number of events= 7
============================
TCGA-COAD ELOVL5
[1] 433
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.06 0.368 0.767
strata=LOW 12 4 2.94 0.383 0.767
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7503 2.1177 0.8757 0.857 0.392
Likelihood ratio test=0.78 on 1 df, p=0.377
n= 24, number of events= 6
============================
TCGA-COAD YY1AP1
[1] 434
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.23 0.0159 0.0346
strata=LOW 12 3 2.77 0.0184 0.0346
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1522 1.1644 0.8195 0.186 0.853
Likelihood ratio test=0.03 on 1 df, p=0.8527
n= 24, number of events= 6
============================
Display the results only for genes where a significant difference in survival has been reported.
significant_genes [1] "TIMP1" "MMD" "PCAT1" "HELLS" "ATG5" "PRR5" "MYB" "GSK3B" "ALOX12" "KDM5A" "SNCA" "KDM6B" "HSPA5" "NOX1" "PVT1" "YAP1" "IREB2" "MAPK9" num_significant_genes <- length(significant_genes)
if (num_significant_genes > 0) {
for (i in 1 : num_significant_genes) {
project <- significant_projects[[i]]
gene <- significant_genes[[i]]
cat(project, gene, "\n\n")
gene_df <- construct_gene_df(gene, project)
fit <- compute_surival_fit(gene_df)
survival <- compute_survival_diff(gene_df)
cox <- compute_cox(gene_df)
print(survival)
cat("\n")
print(cox)
print(plot_survival(fit))
cat("\n\n============================\n\n")
}
}TCGA-COAD TIMP1 Warning: Loglik converged before variable 1 ; coefficient may be infinite. Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 2.38 5.51 9.2
strata=LOW 12 0 3.62 3.62 9.2
Chisq= 9.2 on 1 degrees of freedom, p= 0.002
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.173e+01 3.653e-10 1.714e+04 -0.001 0.999
Likelihood ratio test=11.17 on 1 df, p=0.0008311
n= 24, number of events= 6
============================
TCGA-COAD MMD
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 5.62 1.22 4.44
strata=LOW 12 5 2.38 2.89 4.44
Chisq= 4.4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.6070 4.9877 0.8434 1.905 0.0567
Likelihood ratio test=4.15 on 1 df, p=0.04173
n= 24, number of events= 8
============================
TCGA-COAD PCAT1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 3.17 1.49 4.11
strata=LOW 12 5 2.83 1.67 4.11
Chisq= 4.1 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.956 7.074 1.122 1.744 0.0812
Likelihood ratio test=4 on 1 df, p=0.04557
n= 24, number of events= 6
============================
TCGA-COAD HELLS
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.73 0.802 4.09
strata=LOW 12 3 1.27 2.352 4.09
Chisq= 4.1 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.156e+01 2.305e+09 2.372e+04 0.001 0.999
Likelihood ratio test=5.16 on 1 df, p=0.02312
n= 24, number of events= 5
============================
TCGA-COAD ATG5
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.77 1.77 4.32
strata=LOW 12 4 2.23 1.40 4.32
Chisq= 4.3 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.164e+01 2.491e+09 2.394e+04 0.001 0.999
Likelihood ratio test=5.36 on 1 df, p=0.02063
n= 24, number of events= 4
============================
TCGA-COAD PRR5
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.2 1.48 4.53
strata=LOW 12 0 1.8 1.80 4.53
Chisq= 4.5 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.170e+01 3.768e-10 2.416e+04 -0.001 0.999
Likelihood ratio test=5.52 on 1 df, p=0.01875
n= 24, number of events= 4
============================
TCGA-COAD MYB
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 4.38 1.29 5.38
strata=LOW 12 4 1.62 3.48 5.38
Chisq= 5.4 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.224 9.244 1.139 1.952 0.0509
Likelihood ratio test=5.02 on 1 df, p=0.02501
n= 24, number of events= 6
============================
TCGA-COAD GSK3B
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 2.59 2.59 7.45
strata=LOW 12 4 1.41 4.79 7.45
Chisq= 7.5 on 1 degrees of freedom, p= 0.006
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.204e+01 3.738e+09 2.218e+04 0.001 0.999
Likelihood ratio test=8.44 on 1 df, p=0.003673
n= 24, number of events= 4
============================
TCGA-COAD ALOX12
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 6 3.03 2.91 6.02
strata=LOW 12 0 2.97 2.97 6.02
Chisq= 6 on 1 degrees of freedom, p= 0.01
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.124e+01 5.971e-10 1.655e+04 -0.001 0.999
Likelihood ratio test=8.32 on 1 df, p=0.003917
n= 24, number of events= 6
============================
TCGA-COAD KDM5A
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 2.95 1.29 5.56
strata=LOW 12 3 1.05 3.59 5.56
Chisq= 5.6 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.202e+01 3.667e+09 2.558e+04 0.001 0.999
Likelihood ratio test=6.3 on 1 df, p=0.01209
n= 24, number of events= 4
============================
TCGA-COAD SNCA
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 1.75 2.91 5.42
strata=LOW 12 0 2.25 2.25 5.42
Chisq= 5.4 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.166e+01 3.921e-10 2.057e+04 -0.001 0.999
Likelihood ratio test=6.95 on 1 df, p=0.008381
n= 24, number of events= 4
============================
TCGA-COAD KDM6B
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 1.84 2.52 4.01
strata=LOW 12 1 3.16 1.47 4.01
Chisq= 4 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.9287 0.1453 1.1190 -1.724 0.0848
Likelihood ratio test=3.91 on 1 df, p=0.04806
n= 24, number of events= 5
============================
TCGA-COAD HSPA5
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 1.29 5.67 8.16
strata=LOW 12 2 4.71 1.56 8.16
Chisq= 8.2 on 1 degrees of freedom, p= 0.004
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.65741 0.07013 1.15593 -2.299 0.0215
Likelihood ratio test=6.98 on 1 df, p=0.008225
n= 24, number of events= 6
============================
TCGA-COAD NOX1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 2.212 2.21 8.91
strata=LOW 12 3 0.788 6.22 8.91
Chisq= 8.9 on 1 degrees of freedom, p= 0.003
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.316e+01 1.147e+10 3.212e+04 0.001 0.999
Likelihood ratio test=8.6 on 1 df, p=0.003355
n= 24, number of events= 3
============================
TCGA-COAD PVT1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.2 2.68 4.53
strata=LOW 12 1 2.8 1.15 4.53
Chisq= 4.5 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.172e+01 3.695e-10 2.419e+04 -0.001 0.999
Likelihood ratio test=5.54 on 1 df, p=0.01861
n= 24, number of events= 4
============================
TCGA-COAD YAP1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 2.92 2.92 7.32
strata=LOW 12 5 2.08 4.12 7.32
Chisq= 7.3 on 1 degrees of freedom, p= 0.007
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.170e+01 2.668e+09 1.877e+04 0.001 0.999
Likelihood ratio test=9.02 on 1 df, p=0.002666
n= 24, number of events= 5
============================
TCGA-COAD IREB2
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 0 1.74 1.74 4.15
strata=LOW 12 4 2.26 1.34 4.15
Chisq= 4.2 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.158e+01 2.357e+09 2.378e+04 0.001 0.999
Likelihood ratio test=5.22 on 1 df, p=0.02238
n= 24, number of events= 4
============================
TCGA-COAD MAPK9
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 1 4.77 2.98 10.2
strata=LOW 12 6 2.23 6.35 10.2
Chisq= 10.2 on 1 degrees of freedom, p= 0.001
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.190e+01 3.231e+09 1.761e+04 0.001 0.999
Likelihood ratio test=11.97 on 1 df, p=0.0005413
n= 24, number of events= 7
============================
De La Salle University, Manila, Philippines, gonzales.markedward@gmail.com↩︎
De La Salle University, Manila, Philippines, anish.shrestha@dlsu.edu.ph↩︎
---
title: "Survival Analysis"
subtitle: "Colorectal Cancer | Ferroptosis | Unique Genes per RCD Type | Gene Expression of Tumor Samples"
author: 
  - Mark Edward M. Gonzales^[De La Salle University, Manila, Philippines, gonzales.markedward@gmail.com]
  - Dr. Anish M.S. Shrestha^[De La Salle University, Manila, Philippines, anish.shrestha@dlsu.edu.ph]
output: html_notebook
---

## I. Preliminaries

### Loading libraries

```{r, warning=FALSE, message=FALSE}
library("tidyverse")
library("tibble")
library("msigdbr")
library("ggplot2")
library("TCGAbiolinks")
library("RNAseqQC")
library("DESeq2")
library("ensembldb")
library("purrr")
library("magrittr")
library("vsn")
library("matrixStats")
library("dplyr")
library("grex")
library("survminer")
library("survival")
```

## II. Downloading the TCGA gene expression data 

Create a function for downloading TCGA gene expression data. 

For more detailed documentation, refer to `2. Differential Gene Expression Analysis - TCGA.Rmd`.

```{r}
query_and_filter_samples <- function(project) {
  query_tumor <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = "Primary Tumor"
  )
  tumor <- getResults(query_tumor)

  query_normal <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = "Solid Tissue Normal"
  )
  normal <- getResults(query_normal)

  submitter_ids <- inner_join(tumor, normal, by = "cases.submitter_id") %>%
    dplyr::select(cases.submitter_id)
  tumor <- tumor %>%
    dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
  normal <- normal %>%
    dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)

  samples <- rbind(tumor, normal)
  unique(samples$sample_type)

  query_project <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = c("Solid Tissue Normal", "Primary Tumor"),
    barcode = as.list(samples$sample.submitter_id)
  )

  # If this is your first time running this notebook (i.e., you have not yet downloaded the results of the query in the previous block),
  # uncomment the line below

  # GDCdownload(query_project)

  return(list(samples = samples, query_project = query_project))
}
```

Download the TCGA gene expression data for colorectal cancer (TCGA-COAD).

```{r, echo = TRUE, message = FALSE, results="hide"}
projects <- c("TCGA-COAD")

with_results_projects <- c()

samples <- list()
project_data <- list()

for (project in projects) {
  result <- tryCatch(
    {
      result <- query_and_filter_samples(project)
      samples[[project]] <- result$samples
      project_data[[project]] <- result$query_project

      with_results_projects <- c(with_results_projects, project)
    },
    error = function(e) {

    }
  )
}
```

Running the code block above should generate and populate a directory named `GDCdata`.

## III. Data preprocessing

Construct the RNA-seq count matrix for each cancer type.

```{r, echo = TRUE, message = FALSE, results="hide"}
tcga_data <- list()
tcga_matrix <- list()

projects <- with_results_projects
for (project in projects) {
  tcga_data[[project]] <- GDCprepare(project_data[[project]], summarizedExperiment = TRUE)
}
```

```{r}
for (project in projects) {
  count_matrix <- assay(tcga_data[[project]], "unstranded")

  # Remove duplicate entries
  count_matrix_df <- data.frame(count_matrix)
  count_matrix_df <- count_matrix_df[!duplicated(count_matrix_df), ]
  count_matrix <- data.matrix(count_matrix_df)
  rownames(count_matrix) <- cleanid(rownames(count_matrix))
  count_matrix <- count_matrix[!(duplicated(rownames(count_matrix)) | duplicated(rownames(count_matrix), fromLast = TRUE)), ]

  tcga_matrix[[project]] <- count_matrix
}
```
Format the `samples` table so that it can be fed as input to DESeq2.

```{r}
for (project in projects) {
  rownames(samples[[project]]) <- samples[[project]]$cases
  samples[[project]] <- samples[[project]] %>%
    dplyr::select(case = "cases.submitter_id", type = "sample_type")
  samples[[project]]$type <- str_replace(samples[[project]]$type, "Solid Tissue Normal", "normal")
  samples[[project]]$type <- str_replace(samples[[project]]$type, "Primary Tumor", "tumor")
}
```

DESeq2 requires the row names of `samples` should be identical to the column names of `count_matrix`.

```{r, echo = TRUE, results="hide"}
for (project in projects) {
  colnames(tcga_matrix[[project]]) <- gsub(x = colnames(tcga_matrix[[project]]), pattern = "\\.", replacement = "-")
  tcga_matrix[[project]] <- tcga_matrix[[project]][, rownames(samples[[project]])]

  # Sanity check
  print(all(colnames(tcga_matrix[[project]]) == rownames(samples[[project]])))
}
```

## IV. Differential gene expression analysis

For more detailed documentation on obtaining the gene set, refer to `7. Differential Gene Expression Analysis - TCGA - Pan-cancer - Unique Genes.Rmd`.

```{r}
RCDdb <- "temp/unique_genes/necroptosis_ferroptosis_pyroptosis/"
```

Write utility functions for filtering the gene sets, performing differential gene expression analysis, plotting the results, and performing variance-stabilizing transformation.

```{r}
filter_gene_set_and_perform_dgea <- function(genes) {
  tcga_rcd <- list()

  for (project in projects) {
    rownames(genes) <- genes$gene_id
    tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
    tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
  }

  dds_rcd <- list()
  res_rcd <- list()

  for (project in projects) {
    print(project)
    print("=============")
    dds <- DESeqDataSetFromMatrix(
      countData = tcga_rcd[[project]],
      colData = samples[[project]],
      design = ~type
    )
    dds <- filter_genes(dds, min_count = 10)
    dds$type <- relevel(dds$type, ref = "normal")
    dds_rcd[[project]] <- DESeq(dds)
    res_rcd[[project]] <- results(dds_rcd[[project]])
  }

  deseq.bbl.data <- list()

  for (project in projects) {
    deseq.results <- res_rcd[[project]]
    deseq.bbl.data[[project]] <- data.frame(
      row.names = rownames(deseq.results),
      baseMean = deseq.results$baseMean,
      log2FoldChange = deseq.results$log2FoldChange,
      lfcSE = deseq.results$lfcSE,
      stat = deseq.results$stat,
      pvalue = deseq.results$pvalue,
      padj = deseq.results$padj,
      cancer_type = project,
      gene_symbol = genes[rownames(deseq.results), "gene"]
    )
  }

  deseq.bbl.data.combined <- bind_rows(deseq.bbl.data)
  deseq.bbl.data.combined <- dplyr::filter(deseq.bbl.data.combined, abs(log2FoldChange) >= 1.5 & padj < 0.05)

  return(deseq.bbl.data.combined)
}
```

```{r}
plot_dgea <- function(deseq.bbl.data.combined) {
  sizes <- c("<10^-15" = 4, "10^-10" = 3, "10^-5" = 2, "0.05" = 1)

  deseq.bbl.data.combined <- deseq.bbl.data.combined %>%
    mutate(fdr_category = cut(padj,
      breaks = c(-Inf, 1e-15, 1e-10, 1e-5, 0.05),
      labels = c("<10^-15", "10^-10", "10^-5", "0.05"),
      right = FALSE
    ))

  top_genes <- deseq.bbl.data.combined %>%
    group_by(cancer_type) %>%
    mutate(rank = rank(-abs(log2FoldChange))) %>%
    dplyr::filter(rank <= 10) %>%
    ungroup()

  ggplot(top_genes, aes(y = cancer_type, x = gene_symbol, size = fdr_category, fill = log2FoldChange)) +
    geom_point(alpha = 0.5, shape = 21, color = "black") +
    scale_size_manual(values = sizes) +
    scale_fill_gradient2(low = "blue", mid = "white", high = "red", limits = c(min(deseq.bbl.data.combined$log2FoldChange), max(deseq.bbl.data.combined$log2FoldChange))) +
    theme_minimal() +
    theme(
      axis.text.x = element_text(size = 9, angle = 90, hjust = 1)
    ) +
    theme(legend.position = "bottom") +
    theme(legend.position = "bottom") +
    labs(size = "Adjusted p-value", fill = "log2 FC", y = "Cancer type", x = "Gene")
}
```

```{r}
perform_vsd <- function(genes) {
  tcga_rcd <- list()

  for (project in projects) {
    rownames(genes) <- genes$gene_id
    tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
    tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
  }

  vsd_rcd <- list()

  for (project in projects) {
    print(project)
    print("=============")
    dds <- DESeqDataSetFromMatrix(
      countData = tcga_rcd[[project]],
      colData = samples[[project]],
      design = ~type
    )
    dds <- filter_genes(dds, min_count = 10)

    # Perform variance stabilization
    dds <- estimateSizeFactors(dds)
    nsub <- sum(rowMeans(counts(dds, normalized = TRUE)) > 10)
    vsd <- vst(dds, nsub = nsub)
    vsd_rcd[[project]] <- assay(vsd)
  }

  return(vsd_rcd)
}
```


#### Ferroptosis

Fetch the gene set of interest.

```{r}
genes <- read.csv(paste0(RCDdb, "Ferroptosis.csv"))
print(genes)
genes$gene_id <- cleanid(genes$gene_id)
genes <- distinct(genes, gene_id, .keep_all = TRUE)
genes <- subset(genes, gene_id != "")
genes
```

Filter the genes to include only those in the gene set of interest, and then perform differential gene expression analysis.

```{r}
deseq.bbl.data.combined <- filter_gene_set_and_perform_dgea(genes)
deseq.bbl.data.combined
```

Plot the results.

```{r}
plot_dgea(deseq.bbl.data.combined)
```
Perform variance-stabilizing transformation for further downstream analysis (i.e., for survival analysis).

```{r, warning=FALSE}
vsd <- perform_vsd(genes)
```

## V. Downloading the clinical data

Download clinical data from TCGA, and perform some preprocessing:
- The `deceased` column should be `FALSE` if the patient is alive and `TRUE` otherwise
- The `overall_survival` column should reflect the follow-up time if the patient is alive and the days to death otherwise

```{r}
download_clinical_data <- function(project) {
  clinical_data <- GDCquery_clinic(project)
  clinical_data$deceased <- ifelse(clinical_data$vital_status == "Alive", FALSE, TRUE)
  clinical_data$overall_survival <- ifelse(clinical_data$vital_status == "Alive",
    clinical_data$days_to_last_follow_up,
    clinical_data$days_to_death
  )

  return(clinical_data)
}
```

```{r}
tcga_clinical <- list()
for (project in projects) {
  tcga_clinical[[project]] <- download_clinical_data(project)
}
```

## VI. Performing survival analysis

Write utility functions for performing survival analysis.


```{r}
construct_gene_df <- function(gene_of_interest, project) {
  gene_df <- vsd[[project]] %>%
    as.data.frame() %>%
    rownames_to_column(var = "gene_id") %>%
    gather(key = "case_id", value = "counts", -gene_id) %>%
    left_join(., genes, by = "gene_id") %>%
    dplyr::filter(gene == gene_of_interest) %>%
    dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "tumor")))

  q1 <- quantile(gene_df$counts, probs = 0.25)
  q3 <- quantile(gene_df$counts, probs = 0.75)
  gene_df$strata <- ifelse(gene_df$counts >= q3, "HIGH", ifelse(gene_df$counts <= q1, "LOW", "MIDDLE"))
  gene_df <- gene_df %>% dplyr::filter(strata %in% c("LOW", "HIGH"))
  gene_df$case_id <- paste0(sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 1), '-',
                          sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 2), '-', 
                          sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 3))
  gene_df <- merge(gene_df, tcga_clinical[[project]], by.x = "case_id", by.y = "submitter_id")
  
  return(gene_df)
}
```

```{r}
compute_surival_fit <- function(gene_df) {
  return (survfit(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}
```

```{r}
compute_cox <- function(gene_df) {
  return (coxph(Surv(overall_survival, deceased) ~ strata, data=gene_df))
}
```

```{r}
plot_survival <- function(fit) {
  return(ggsurvplot(fit,
    data = gene_df,
    pval = T,
    risk.table = T,
    risk.table.height = 0.3
  ))
}
```

```{r}
compute_survival_diff <- function(gene_df) {
  return(survdiff(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}
```

Perform survival analysis by testing for the difference in the Kaplan-Meier curves using the G-rho family of Harrington and Fleming tests: https://rdrr.io/cran/survival/man/survdiff.html

```{r}
significant_projects <- c()
significant_genes <- c()

ctr <- 1
for (project in projects) {
  for (gene in c(genes$gene)) {
    cat(project, gene, "\n\n")
    error <- tryCatch (
      {
        gene_df <- construct_gene_df(gene, project)
      },
      error = function(e) {
        cat("\n\n============================\n\n")
        e
      }
    )
    
    if(inherits(error, "error")) next

    if (nrow(gene_df) > 0) {
      fit <- compute_surival_fit(gene_df)
      tryCatch (
        {
          survival <- compute_survival_diff(gene_df)
          cox <- compute_cox(gene_df)
          print(ctr)
          ctr <- ctr + 1
          print(survival)
          cat("\n")
          print(cox)
          print(plot_survival(fit))
          if (pchisq(survival$chisq, length(survival$n)-1, lower.tail = FALSE) < 0.05) {
            significant_projects <- c(significant_projects, project)
            significant_genes <- c(significant_genes, gene)
          }
        },
        error = function(e) {
        }
      )
      
    }
    
    cat("\n\n============================\n\n")
  }
}
```

Display the results only for genes where a significant difference in survival has been reported.

```{r}
significant_genes
```

```{r}
num_significant_genes <- length(significant_genes)

if (num_significant_genes > 0) {
  for (i in 1 : num_significant_genes) {
    project <- significant_projects[[i]]
    gene <- significant_genes[[i]]
    
    cat(project, gene, "\n\n")
    gene_df <- construct_gene_df(gene, project)
    
    fit <- compute_surival_fit(gene_df)
    survival <- compute_survival_diff(gene_df)
    cox <- compute_cox(gene_df)
    print(survival)
    cat("\n")
    print(cox)
    print(plot_survival(fit))
    
    cat("\n\n============================\n\n")
  } 
}
```